Tirofiban
Tirofiban is an antiplatelet drug. Tirofiban reduces the frequency of thrombotic
cardiovascular events. These events combine endpoint of death, myocardial infarction, or
refractory ischemia/repeat the cardiac procedure in patients with non-ST elevation acute
coronary syndrome. Its actions prevent blood from clotting during episodes of chest pain or a
heart attack, or during procedures related to the blocked coronary artery. It is a non-peptide
reversible antagonist of the platelet glycoprotein receptor. It works by inhibiting platelet
aggregation.
Tirofiban is marketed under the brand name Aggrastat amongst others.
Baxter Healthcare Corporation first filed for a patent of Tirofiban. It was first approved in the
US in 2000. Medicare Pharma in the USA markets it.
Forms and Dose:
Tirofiban is available for premixed IV infusion solution in 5mg/100mL and 12.5mg/250mL,
and for IV solution vials in 5mg/100mL vialand 3.75mg/15mL bolus vials.
In the treatment of Non-ST Elevation Acute Coronary Syndrome, the recommended loading
dose is 25 mcg per kilo IV infused within 5 minutes, to reduce the rate of thrombotic
cardiovascular events. The post-loading dose is limited to 0.15 mcg per kilo per minute of IV
for up to 18 hr.
The price of Tirofiban:
In the USA, the average price consumers pay for the intravenous solution of 250 mcg/mL is
around $68 for a supply of 15 millilitres. However, the price in India for a generic version of
this medicine is lower at USD200 for a supply of 50ml.
How does Tirofiban work?
Tirofiban’s action provide relief by preventing the formation of blood clots during chest pain
or heart attack episodes, or while undergoing a procedure related to the blocked coronary
artery. Its primary action inhibits platelet aggregation. When administered intravenously, as
per the recommended regimen, more than 90% inhibition is attained within 30-minutes of the
infusion.
Finding Tirofiban Manufacturers and Suppliers:
The best way to find and gain access to Tirofiban’s manufacturers and suppliers is to make
through Pipelinepharma's global B2B online marketplace for medicines and other
pharmaceuticals. In the normal way, finding trusted manufacturers and supplies of specific
drugs like Tirofiban can be a time-consuming challenge, but with Pipelinepharma's simple
search engine and network of proven partners, the whole process becomes a lot easier.
The patient needs to do to get started is to make use of our integrated search engine and
start looking for suppliers or manufacturers of this drug to work with and fine-tune his search
results using various filters too, letting him search for it from specific countries.