Tirofiban is an antiplatelet drug. Tirofiban reduces the frequency of thrombotic
cardiovascular events. These events combine endpoint of death, myocardial infarction, or
refractory ischemia/repeat the cardiac procedure in patients with non-ST elevation acute
coronary syndrome. Its actions prevent blood from clotting during episodes of chest pain or a
heart attack, or during procedures related to the blocked coronary artery. It is a non-peptide
reversible antagonist of the platelet glycoprotein receptor. It works by inhibiting platelet
Tirofiban is marketed under the brand name Aggrastat amongst others.
Baxter Healthcare Corporation first filed for a patent of Tirofiban. It was first approved in the
US in 2000. Medicare Pharma in the USA markets it.
Forms and Dose:
Tirofiban is available for premixed IV infusion solution in 5mg/100mL and 12.5mg/250mL,
and for IV solution vials in 5mg/100mL vialand 3.75mg/15mL bolus vials.
In the treatment of Non-ST Elevation Acute Coronary Syndrome, the recommended loading
dose is 25 mcg per kilo IV infused within 5 minutes, to reduce the rate of thrombotic
cardiovascular events. The post-loading dose is limited to 0.15 mcg per kilo per minute of IV
for up to 18 hr.
The price of Tirofiban:
In the USA, the average price consumers pay for the intravenous solution of 250 mcg/mL is
around $68 for a supply of 15 millilitres. However, the price in India for a generic version of
this medicine is lower at USD200 for a supply of 50ml.
How does Tirofiban work?
Tirofiban’s action provide relief by preventing the formation of blood clots during chest pain
or heart attack episodes, or while undergoing a procedure related to the blocked coronary
artery. Its primary action inhibits platelet aggregation. When administered intravenously, as
per the recommended regimen, more than 90% inhibition is attained within 30-minutes of the
Finding Tirofiban Manufacturers and Suppliers:
The best way to find and gain access to Tirofiban’s manufacturers and suppliers is to make
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pharmaceuticals. In the normal way, finding trusted manufacturers and supplies of specific
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The patient needs to do to get started is to make use of our integrated search engine and
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