● Drug Name: Pregabalin Manufacturer
● Chemical formulation: C8H17NO2
● Active ingredient: Pregabalin
● Common/generic brand name: LYRICA
● Approved by FDA or not: Yes
● Commonly marketed in: USA
● Density: 0.997±0.06 g/cm3(Predicted)
What is Pregabalin?
Pregabalin is an anticonvulsant derivative of the neurotransmitter Gamma Amino Butyric Acid (GABA) which targets neuronal activity. The purpose of this drug is to deal with neuropathic pain in adults mainly caused due to Diabetes, Shingles infection, or in case of any damage to the Spinal Cord. It is also used for the treatment of Generalized Anxiety Disorder (GAD) in adults and Fibromyalgia.
Pregabalin may show variation or changes in its effects if it is used chronically or with other addictive substances like other drugs or alcohol. The doctor’s prescription is mandatory for this drug. Pregabalin may show adverse effects as a result of drug interaction or may inhibit the potential of other medicinal drugs or herbs.
General drug sources for Pregabalin:
Pregabalin is retailed by many sources which include Upjohn, Actavis Elizabeth, Alembic Pharms Ltd, Alkem Labs Ltd, Amneal Pharms Co, Celltrion, Cipla, Cspc Ouyi, Dr. Reddys, Hetero Labs Ltd Iii, Hikal, Invagen Pharms, MSN, Mylan, Rising, Sciegen Pharms Inc, Shuangcheng, Sun Pharm, Teva Pharms, Alvogen Pine Brook, and Apotex.
Pregabalin is available in multiple forms:
Pregabalin is administered orally in capsules and liquid form. A rare form of this drug is available as an extended-release tablet, ingested orally. Capsules are the most frequently used form of Pregabalin. They are prescribed in different dosages depending on the disease.
How should Pregabalin be used?
Pregabalin is administered in capsules with dosages that vary uniformly such as 25 mg, 50 mg, 75 mg, 100 mg, 150 mg, 200 mg, 225 mg, and 300 mg. In liquid form, Pregabalin is available as 20mg/mL. It has to be taken in a combination with any other drug.
Pregabalin can be taken with a glass of water or juice. It may be taken with or without food. Ideally, the dose should be split three times a day and there should be uniform intervals in between.
The drug is mainly prescribed for adults aged 18-64yrs and is prohibited for patients below 17yrs. Patients above 64 years are primarily monitored for their renal function which has to respond significantly to eliminate the drug.
Initially, the dosage starts from 50mg which is increased gradually by the doctor once the response to the dose is monitored.
It is suggested not to stop Pregabalin abruptly, instead, decrease the dose gradually to avoid any adverse effects. The generally prescribed doses for the mentioned disease are as follows:
For diabetic peripheral neuropathy: 50 mg is taken three times per day.
A maximum dose of 300mg per day is allowed.
Dosage for shingles: a total of 150–300 mg per day, either split into two doses or three doses with a maximum dose of 600mg per day allowed.
Dosage for nerve pain due to spinal cord injury: 75 mg taken two times per day with a maximum dose of 600mg.
Dosage for fibromyalgia: 75 mg taken two times with a maximum dose of 450mg per day.
Pregabalin Manufacturers & Wholesalers List
VPL Chemicals Pvt. Lmt
Shanghai Ansion Pharma Technology
Hefei TNJ Chemical Industry Cooperation
Sai Teja Drugs and Intermediates Pvt Ltd
Wuhan Benjamin Pharmaceutical Chemical Co., Ltd
Hermes Chemical Company Private Limited
Liven Pharma (Pvt.) Ltd.
Hangzhou Pharma & Chem Co., Ltd.
Zhejiang Jiuzhou Pharmaceutical Co., Ltd.
Eastsky Pharm (Anhui) Technology Co., Ltd
Cost of Pregabalin:
The cost of Pregabalin per unit capsule in the USA is as follows: 25mg capsule costs $1.43, $0.78 for 50mg, 75mg, 100mg and 150mg, $1.71 for 200mg, $2.10 for 225mg and $1.76 for 300mg
How to buy pregabalin on Pipelinepharma?
Pregabalin is widely available for purchase by numerous sellers and manufacturers which may include fraud sellers which may lead you to some risks which are neglected by the sellers for the sake of generating a maximum number of customers. Pipelinepharma provides you a reliable manufacturer through which you will not be misguided or face any inconvenience. Saving your time and energy you will be dealing with licensed sellers, assuring you the most suitable quality product. Pipelinepharma plays a vigilant role in connecting you with the best sellers of Pregabalin in any country of the world. You can easily place your query or place your order or ask anything of your concern. Pipelinepharma does not only cater to distributors and buyers but also has a policy of free-of-cost registration for drug whole-sellers.
Like other drugs, Pregabalin also has some side effects which mostly manifest in the initial doses. These side effects appear in 1% of patients and are usually mild which restore with time. These include headaches, feeling lethargic, diarrhea, trouble in concentration, amnesia (memory loss), hallucinations, xerostomia (dry mouth), hazy vision, increased weight, or sometimes swelling of upper and lower limbs. You can consult your doctor if these reactions don’t get rectified with time. Pregabalin may alter blood sugar levels in diabetic patients therefore it is suggested to monitor these levels once you start taking the drug.
Serious allergic reactions may prove to be life-threatening. These reactions include symptoms like frequent panic attacks, swelling of the face, shortness of breath. Other reactions include suicidal attempts, aggressive behavior, hyper manic or hypomanic episodes, and chest pain.
Special Warning or precaution for use:
Pregabalin is highly prohibited for patients that are hypersensitive to an active ingredient or other constituents present in it. It may lead to serious allergic reactions like swelling of face, mouth, lips, tongue, and gums, rashes or hives on the skin, or shortness of breath mostly manifesting as tightness of chest or throat. Immediately consult your doctor if these reactions occur otherwise, it may prove fatal.
Effect of Pregabalin on Pregnancy and Breastfeeding
Pregabalin shows no meaningful evidence of harmful effects in pregnant women, but it is suggested to consider the risk/benefit ratio. If a woman is pregnant and suffering from seizures, she should not neglect the intake of the drug as seizures are important to treat. To avoid any inconvenience, consult with your doctor before and after conceiving.
Pregabalin is secreted in breast milk and therefore, may harm the baby. It is better to consider your doctor’s advice, and he may withdraw or continue Pregabalin based on the benefits and risks of the drug.
FAQ About Pregabalin:
1.Does pregabalin act on sleep-cycles? Pregabalin acts as a sleep inducer hence results in a long and effective sleep cycle.
2.What is the best time for pregabalin to act effectively?
Pregabalin should be taken with food or with water, however, it is better to take it after an evening meal.
3.Is pregabalin used for long-term anxiety disorders?
Pregabalin is a neurotransmitter that best controls and cures anxiety disorders.
4.How much time does pregabalin take to work in anxiety disorders?
Pregabalin shows relief in a patient's symptoms of anxiety in four weeks.
5.What is the mode of action of pregabalin in a patient’s body?
Being a neurotransmitter, it targets neuronal activity, nulling the pain stimulus received from the damaged nerve.