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Tigecycline manufacturers

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Country of origin : Portugal

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Powder for solution for infusion 50 mg/5 ml

Dossier type
Dossier status
Ready to file
Country of origin
European Union
GMP approvals
Unavailable markets
Portugal , Saudi Arabia , Vietnam , Serbia
MAs for sale
Saudi Arabia
Manufacturer #437
A pharmaceutical manufacturer based in the EU that is active in 40+ countries selling its products in Europe, North America, LATAM, Africa, Middle East, and Asia for 40+ years. Main therapeutics areas include the nervous system, cardiometabolic, and women’s health. The company's production lines are GMP-compliant. The main dosage forms are solid, semi-solid, liquid, and suspension. The company owns branches in the EU, Africa, and LATAM.

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Tigecycline Manufacturers

Tigecycline is a broad-spectrum antibiotic like tetracycline and belongs to the class of drugs called antibiotics. Tigecycline is the first clinically-available drug in a class of antibiotics called the Glycylcyclines which acts as tetracycline antibiotics. Tigecycline is indicated for the treatment of infections of the skin, digestive system and pneumonia caused by many different bacteria. This medication is used to treat when other antibiotics fail to work. Manufacturers market Tigecycline under the Brand name of Tygacil. Tigecycline is advised as a prescription product as well as generic prescription product.

This medication is available in dosage form of Injection (powder for solution, lyophilized powder for solution), and is available in dosage strengths of 50 mg, 50 mg/5mL which is administered through intravenous route by healthcare professionals. Tigecycline injection is supplied in a single dose of 5 mL glass vial or 10 mL glass vial in a box containing 10 vials. Before using this medication, the risk of taking the drug must be weighed against the benefits it provides. It is always recommended to consult a physician before taking tigecycline as this medication may interact with other drugs and health problems. The usual recommended dose of Tigecycline injection is an initial dose of 100 mg, followed by 50 mg twice a day. Tigecycline injection should be administered intravenously over approximately 30 to 60 minutes.

For the treatment of complicated skin and skin infections or for complicated intra-abdominal infections, tigecycline treatment duration is 5 to 14 days and for community-acquired bacterial pneumonia the treatment duration is 7 to 14 days. To have the maximum effect, it should be used at evenly spaced time and the medication should be taken at the same time every day, and tigecycline should be used even if the symptoms disappear and one must continue until the full prescribed dose is finished. In patients with severe hepatic impairment, the initial dose of tigecycline 100 mg is administered followed by a reduced maintenance dose of 25 mg twice daily. Tigecycline injection should be stored at room temperature not exceeding 25° C (77° F) for a day once it is reconstituted. Before reconstitution, tigecycline should be stored at 20° C to 25° C (68° F to 77° F).

Wholesale Price of Tigecycline

The wholesale price for tigecycline intravenous powder for injection 50 mg is around $ 792 for a supply of 10 powder for injection with per unit cost available for $ 79.22 depending on the pharmacy once visit.

Tigecycline - Mechanism of Action

Tigecycline is a bactericidal and broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. Tigecycline mode of action depends on binding to the 30S ribosomal subunit and blocking entry of amino-acyl tRNA molecule of the ribosome which inhibits protein translation in bacteria and prevents incorporation of amino acid residues into the elongating peptide chains. Tigecycline is considered as bacteriostatic however tigecycline has demonstrated bactericidal activity against isolates of S. pneumoniae and L. pneumophila.

Finding Tigecycline Manufacturers and Suppliers

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