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Tazobactam manufacturers

206 products found

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206 products found

tazobactam + ceftriaxone

Vials, injection 125 mg + 1000 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Manufacturer #18132

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piperacillin + tazobactam

Injection 2.25 g, 3.375 g, 4.5 g, 40.5 g

Dossier type
US CTD
Dossier status
Ready to file
Country of origin
European Union
GMP approvals
FDA
Manufacturer #17548
A pharmaceutical manufacturer based in the EU that is active in 20+ countries selling its products in Europe, North America, and Asia for 100+ years. Main therapeutic areas include gastroenterology, anti-infectious drugs, inflammation and pain, and nutraceuticals. The main dosage forms are injectable, oral, and topical. They are produced in cGMP-compliant manufacture.

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piperacillin + tazobactam

Powder for solution for infusion 4 g + 0.5 g

Dossier type
EU CTD
Dossier status
Ready to file
Country of origin
European Union
GMP approvals
EU GMP
Manufacturer #17473
A pharmaceutical manufacturer based in the EU that is active in 40+ countries worldwide selling its products in Europe, the Middle East, LATAM, and Asia for 50+ years. The company has partnerships in the EU for production that comply with GMP standards. Key production lines include pharmaceutical products, nutraceuticals, medical devices, and cosmetics. Therapy areas include anti-infectives, anti-inflammatory and dermatological. The company has its R&D and regulatory affairs department for CTD dossier and marketing authorization management.

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TAZOBACTAM

Tazobactam is a penicillin that is heavily modified and a sulfone. It inhibits the action of bacterial β-lactamases, especially those belonging to the SHV-1 and TEM groups. Simply put, it is an ingredient that can be added to certain antibiotics to make them less vulnerable to bacteria's antimicrobial resistance. Tazobactam is commonly used as in its sodium salt, tazobactam sodium form. Tazobactam is combined with the extended-spectrum β-lactam antibiotic piperacillin in the drug piperacillin/tazobactam, used in infections due to Pseudomonas aeruginosa. Tazobactam expands the spectrum of activity by making it effective against organisms that express β-lactamase and would normally degrade piperacillin. Piperacillin with tazobactam is penicillin antibiotic used to treat different infections caused by bacteria, like stomach, skin, pneumonia, and severe vaginal infections. Tazobactam is sold under the brand name Zerbaxa, Zosyn amongst others. Taiho Pharmaceutical Company filed some of the first patent related to making this medicine in 1982 and came into medical use in 1992. Since then the patents have expired, many other companies have made their formulations of this medicine.

Forms and dose:

Piperacillin is sold as Piperacillin/Tazobactam 4 g/0.5 g Powder for Solution for Infusion, where 1 vial has 4 g piperacillin as sodium salt and 0.5 g tazobactam as the sodium salt. The usual recommended adult dose is 4 g piperacillin / 0.5 g tazobactam administered every eight hours. While treating nosocomial pneumonia and bacterial infections in neutropenic patients, the usual recommended adult dose is 4 g piperacillin / 0.5 g tazobactam administered every six hours. For children under 2 years of age, the dose is 80 mg Piperacillin / 10 mg Tazobactam per kilo of body weight given every six hours for treating Neutropenic children with fever suspected to be due to bacterial infections. For treating Complicated intra-abdominal infections, the recommended dose is 100 mg Piperacillin / 12.5 mg Tazobactam per kilo of body weight given every eight hours.

The price of Tazobactam

In the USA, depending on the pharmacy and brands, for a supply of 10 powder for injection, the consumers have to pay between $69.30 and $138.60. the same supply of 10 powder for injection will cost around USD60 in India.

How does it work?

Tazobactam works by inhibiting the action of bacterial beta-lactamase producing organisms. These are normally resistant to beta-lactam antibiotics. Tazobactam augments the efficacy of antibiotic that would otherwise not be effective in treating certain infections.

Finding Tazobactam Manufacturers and Suppliers

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