Sevelamer Carbonate Manufacturer
Drug Name: Sevelamer Carbonate
Chemical formulation: C7H14ClNO4
Active ingredient: Sevelamer Carbonate
Common/generic brand name: Sevelamer Carbonate
Approved by FDA or not: FDA approved
Commonly marketed in: India, Australia, Canada, China, European Union, the United Kingdom, and the United States.
Density: Sevelamer is available in 400mg and 800mg tablet dosages, as well as 800mg and 2400mg powder packets for oral suspension. The suggested Initial Amount for patients with chronic kidney disease on dialysis who are not using phosphate binder is 1600 mg every 8 hours; however, this dose can vary depending on the concentration as determined by the doctor. The substitute dose for people transitioning from calcium acetate is 800 mg for 667 mg Ca-acetate, 1600 mg for 1334 mg Ca-acetate, or 2400 mg for 2001 mg Ca-acetate.
What is the Sevelamer Carbonate?
Individuals on dialysis who have chronic kidney disease are given Sevelamer Carbonate to manage high phosphorus levels in their blood. Phosphate binder Sevelamer attaches to dietary phosphate and inhibits it from being absorbed. Polyallylamine is conjugated with epichlorohydrin to form Sevelamer Carbonate. In the gut, several amine groups are partially protonated and bind with phosphate ions via hydrogen and ionic bonding, lowering serum uric acid considerably. It, on the other hand, has no negative consequences and has a number of positive ones, such as lowering hyperuricemia, uric acid nephrolithiasis, and arthritis.
Sevelamer Carbonate is available in multiple forms:
Sevelamer Carbonate is available in tablets and powder.
Sevelamer Carbonate Manufacturers & Wholesalers List
Currently, we haven't found any verified Sevelamer Carbonate manufacturers or Sevelamer Carbonate suppliers from our global list of sellers. For more information about sourcing wholesale supplies of Sevelamer Carbonate, please speak to one of Pipelinepharma's customer support representatives on +370-5-207-5842 or send an email to
[email protected]. We will get back to you as soon as possible
How to buy Sevelamer Carbonate on Pipelinepharma?
Making use of Pipelinepharma's worldwide B2B online platform for medications and other pharmaceuticals is the best method to identify and gain access to several carbonate suppliers and manufacturers. Finding reliable producers of specialized pharmaceuticals like sevelamer carbonate could be difficult in the past, but with Pipelinepharma's straightforward search engine and database of proven partners, the process is a lot easier now. To get started, simply use our inbuilt search engine to look for manufacturers and distributors of sevelamer carbonate with which to collaborate. You may also use other criteria to narrow down your search results, allowing you to look for several carbonates from certain countries.
How to use Sevelamer Carbonate?
Sevelamer is a non-absorbed bound crosslinked polymer with several amines spaced from the polymer backbone with one carbon. In the gut, their protonated forms establish ionic and hydrogen bonds with phosphate molecules. Its activities bind phosphate in the gastrointestinal tract, reducing absorption. It reduces the amount of phosphate in the blood. Its effects cause advanced glycation end products to be sequestered in the gut, blocking their absorption into the bloodstream. These chemicals generate oxidative stress, which damages the beta cells in the pancreas that make insulin.
Sevelamer Carbonate Side effects -
Common side effects:
It is possible to experience headaches, diarrhea, stomach discomfort, nausea, puking, congestion, gas, or constipation. Notify the doctor or pharmacist right away if any of these side effects remain or intensify.
Uncommon Side Effects:
If anyone suffers any significant side effects, such as issues with your dialysis access sites, severe nausea to urinate, symptoms of abdomen bleeding or ulcers (like black/bloody feces, puke that looks like ground coffee, abdomen pain, disorientation).
Not Known and Rare Effects:
This medicine seldom causes a severe allergic reaction. However, if anyone detects any symptoms of a major allergic response, such as redness, itchiness, extreme dizziness, or problems breathing, seek medical treatment right once.
Special Warning or precaution for use
The usage of the tablet formulation of sevelamer has been linked to cases of dysphagia and esophageal tablet retention, with some patients requiring hospitalization and intervention. In patients with a history of swallowing problems, sevelamer suspension may be used.
Effect of Sevelamer Carbonate on Pregnancy and Breastfeeding
Sevelamer carbonate is not taken systemically after oral treatment, therefore it is unlikely that prenatal exposure to the drug will occur. Considerations in Clinical Practice, in pregnant women, sevelamer carbonate may lower serum levels of fat-soluble vitamins and folic acid. Sevelamer Carbonate is not concentrated by the mother after oral treatment, and it is unlikely that the kid will be exposed to Sevelamer Carbonate through breastfeeding. Considerations in Clinical Practice In pregnant women, sevelamer carbonate may lower serum concentrations of fat-soluble vitamins and folic acid.
FAQ About Sevelamer Carbonate
1.What should One stay away from while on sevelamer?
People could be taking additional medications that users shouldn't use at the same time. When someone uses sevelamer, the body has a harder time absorbing some medications, making them less useful:
Use ciprofloxacin (Cipro) at least two hours beforehand or 6 hours after patients take sevelamer.
Consume mycophenolate mofetil (CellCept) at least two hours before taking sevelamer.
2.What happens if Someone forgets to take a dose?
As soon as users recall, consume the missed dose. If users miss a dosage, remember to take it with food. If the next scheduled dosage is approaching, avoid the missing dose. To make up for a missed dosage, do not take more medication.
3.Which way should it be stored?
The medicine should be stored in a place where there is no sunlight. The room temperature should be maintained with moisture. Keep the medicine out of the bathroom. The drug should be kept out of reach or out of the hands of the pets and children.
4.What are the contraindications of Sevelamer Carbonate?
In patients with intestinal blockage, Sevelamer Carbonate is not recommended. Individuals who have a known hypersensitivity to sevelamer carbonate, sevelamer hydrochloride, or any of the active ingredients should avoid using Sevelamer Carbonate.