Phosphatidyl choline (PC) is an important type of phospholipid and a major structural
component of cell membranes, where it provides integrity and structure to the all-important
membranes and regulates their fluidity. PC also provides structure to circulating lipoproteins
and is essential for lipid transport and metabolism. As an essential component of bile, PC
facilitates fat emulsification, absorption and transport. Additionally, PC is a constituent of
surfactants in the body, including those of the lungs and gastrointestinal tract, where it
protects these important epithelial-luminal interfaces. The clinical applications of PC
centre on its role in hepatic detoxification and protection, and through its role in providing
choline in the body for lipid metabolism, liver function, homocysteine metabolism, cell
signalling, neurotransmitter synthesis and methylation reactions.[1,3]
1,2-diacyl-:ussn:ueglycero-3-phosphocholine, Fosfatidilcolina, Lipodissolve, Lipolight,
Lipolyse, Lipothérapie, Lipotherapy, Phosphatidyl Choline, Phospholipid, Phospholipide,
Phospholipon, Polyenylphosphatidylcholine, Polyénylphosphatidylcholine, PtdCho.
The name "lecithin" was originally defined from the Greek lekithos (λεκιθος, egg yolk) by
Theodore Nicolas Gobley, a French chemist and pharmacist of the mid-19th century, who
applied it to the egg yolk phosphatidylcholine that he identified in 1847. Gobley eventually
completely described his lecithin from chemical structural point of view, in 1874.
Phosphatidyl cholines are such a major component of lecithin that in some contexts the terms
are sometimes used as synonyms. However, lecithin extracts consist of a mixture of
phosphatidylcholine and other compounds. It is also used along with sodium taurocholate for
simulating fed- and fasted-state biorelevant media in dissolution studies of highly lipophilic
It is chemical contained in eggs, soyabeans, mustards, sunflower , and other foods.It is found
naturally in the body in all cells.
By mouth-Ulcerative colitis—1-6 grams daily taken in divided doses.
How does it work?
The body makes a brain chemical called acetylcholine from phosphatidylcholine.
Acetylcholine is important for memory and other bodily functions. Since phosphatidylcholine
might increase acetylcholine, there is interest in using it for improving memory and for
conditions such as Alzheimer's disease. Some researchers think phosphatidylcholine acts like
a detergent and breaks down fat. A certain form of phosphatidylcholine (polyunsaturated
phosphatidylcholine) might provide protection against liver fibrosis and liver damage caused
by drinking alcohol, although the exact mechanisms are not completely understood.
Phosphatidylcholine might also help to protect the wall of the large intestine in people with a
condition known as ulcerative colitis.