Phosphatidyl choline (PC) is an important type of phospholipid and a major structural component of cell membranes, where it provides integrity and structure to the all-important membranes and regulates their fluidity. PC also provides structure to circulating lipoproteins and is essential for lipid transport and metabolism.[1] As an essential component of bile, PC facilitates fat emulsification, absorption and transport.[2] Additionally, PC is a constituent of surfactants in the body, including those of the lungs and gastrointestinal tract, where it protects these important epithelial-luminal interfaces.[3] The clinical applications of PC centre on its role in hepatic detoxification and protection, and through its role in providing choline in the body for lipid metabolism, liver function, homocysteine metabolism, cell signalling, neurotransmitter synthesis and methylation reactions.[1,3] Other names-- 1,2-diacyl-:ussn:ueglycero-3-phosphocholine, Fosfatidilcolina, Lipodissolve, Lipolight, Lipolyse, Lipothérapie, Lipotherapy, Phosphatidyl Choline, Phospholipid, Phospholipide, Phospholipon, Polyenylphosphatidylcholine, Polyénylphosphatidylcholine, PtdCho. The name "lecithin" was originally defined from the Greek lekithos (λεκιθος, egg yolk) by Theodore Nicolas Gobley, a French chemist and pharmacist of the mid-19th century, who applied it to the egg yolk phosphatidylcholine that he identified in 1847. Gobley eventually completely described his lecithin from chemical structural point of view, in 1874. Phosphatidyl cholines are such a major component of lecithin that in some contexts the terms are sometimes used as synonyms. However, lecithin extracts consist of a mixture of phosphatidylcholine and other compounds. It is also used along with sodium taurocholate for simulating fed- and fasted-state biorelevant media in dissolution studies of highly lipophilic drugs. It is chemical contained in eggs, soyabeans, mustards, sunflower , and other foods.It is found naturally in the body in all cells. Brand names- PHOSCHOL(U.S) HepatoPro Phosphatidylserine Essenvita CHOLINE. Dosage: Adults- By mouth-Ulcerative colitis—1-6 grams daily taken in divided doses. How does it work? The body makes a brain chemical called acetylcholine from phosphatidylcholine. Acetylcholine is important for memory and other bodily functions. Since phosphatidylcholine might increase acetylcholine, there is interest in using it for improving memory and for conditions such as Alzheimer's disease. Some researchers think phosphatidylcholine acts like a detergent and breaks down fat. A certain form of phosphatidylcholine (polyunsaturated phosphatidylcholine) might provide protection against liver fibrosis and liver damage caused by drinking alcohol, although the exact mechanisms are not completely understood. Phosphatidylcholine might also help to protect the wall of the large intestine in people with a condition known as ulcerative colitis.