Omalizumab Manufacturers

Omalizumab is a recombinant DNA-derived humanized monoclonal antibody. Omalizumab is a protein that resembles one type of human protein. Omalizumab is primarily indicated for moderate to severe persistent asthma. This medication is used to decrease the number of asthma attacks. Omalizumab is also used to treat chronic hives without a known cause that cannot successfully be treated with antihistamine medications. Omalizumab is marketed by manufacturers under the Brand name of Xolair. This medication is available in solution, powder for solution, injection solution dosage forms which are administered subcutaneously. Both the powder for solution and injection solution (prefilled syringe) should be administered by a healthcare professional. The injection may take 5-10 seconds to administer. Manufacturers supply Omalizumab with dosage strengths of 75 mg, 150mg/1mL, 202.5 mg/1.4mL Each injectable single-use vial is reconstituted with sterile water for injection and administered as a subcutaneous injection. Each 202.5 mg vial of omalizumab is designed to deliver 150 mg of omalizumab in 1.2 mL after reconstitution with 1.4 mL sterile water for injection. The recommended dose of omalizumab for allergic asthma is 150mg-375mg every 2 to 4 weeks. The dose and frequency are based on body weight and levels of serum IgE, doses greater than 150 mg should be divided and injected at different sites so that no more than 150 mg is administered at each injection site. For chronic hives, the recommended dose is usually once every 4 weeks. This medication is not recommended for allergic asthma in children below 6 years of age as safety and efficacy is not established. The recommended dose for children between 6-12 years is 75 mg - 375 mg every 2-4 weeks. After administration of the dose, as a precaution in case of an allergic reaction, the patient should remain under observation for a certain period of time. The need for continued therapy should be reassessed periodically based on the patient’s disease severity and level of asthma control. Omalizumab should be stored under refrigerated conditions 2° C - 8° C (36 ° F - 46 ° F). This medication is for single use only and contains no preservatives. The solution should be used within 8 hours following reconstitution when stored in the vial at 2° C - 8° C (36 ° F - 46 ° F), or within 4 hours of reconstitution when stored at room temperature. Reconstituted Omalizumab vials should be protected from direct sunlight.

Wholesale Price of Omalizumab

The price of Omalizumab subcutaneous powder for injection 150 mg is around $ 1,187.64 for a supply of 1 powder for injection and these prices are not valid with insurance plans. The current US wholesale prices of Omalizumab average almost $ 1300 per patient per month.

Omalizumab - Mechanism of Action

Omalizumab blocks the receptors on the surfaces of the mast cells and basophils to which antibodies attach, thereby preventing antibodies from attaching to the cells. As a result, the cells do not release their chemicals and the inflammation and allergic reaction are prevented.

Finding Omalizumab Manufacturers and Suppliers

At times we find manufacturers and suppliers by attending conferences, exhibitions, etc. which is not as cost-effective and it also consumes a lot of time, and we are not sure whether we get the trusted suppliers, which is a major constraint. One can avoid this challenge by Pipelinepharma, which helps you in finding the trusted manufacturers and suppliers of Omalizumab. Pipelinepharma, which is a business-to-business (B2B) licensing marketplace for pharmaceutical products that quickly connects the owner with the consumer for business development. One can filter the product names in a unified search engine by its country, category, therapeutic area, forms, dossier, and its status, regulatory filings, approvals, and many more.