Naloxone is a lipophilic compound used to block the effects of opioids (substances that act on opioid receptors to produce morphine-like effects), particularly within the setting of drug overdoses, which are rapidly becoming a leading cause of death worldwide. Naloxone is used for pain relief, including anesthesia.
Naloxone was patented in 1961 by Mozes J. Lewenstein, Jack Fishman, and the company Sankyo and approved for opioid overdose in the United States by the FDA in 1971. From the 90s until 2014, Naloxone kits for opioid abuse had been distributed to medically untrained people by many states, and the CDC estimates over 26,000 cases of opioid overdose have been reversed using the kits. Naloxone is on the World Health Organization's List of Essential Medicines.
Naloxone is a globally found drug and has many brand names that include Narcan, Nalone, Evzio, Prenoxad Injection, Narcanti, Narcotan. Some of Naloxone manufacturers are Akorn, Inc, Mylan Pharmaceuticals Inc, Pfizer Inc, West-Ward Pharmaceuticals. Naloxone suppliers market it under different final dosage forms, such as 0.4mg, 2 mg/0.4 ml intramuscular or subcutaneous injection, 4 mg/0.1 mL nasal spray, or intravenous infusion.
How does Naloxone work?
To treat opioid overdose, an adult patient should take the initial dose of 0.4 mg to 2 mg IV. If there is not the desired response, the doses should be repeated at 2 to 3-minutes intervals. If the treatment is with a nasal spray, the patient should administer one spray intranasally into one nostril. For opioid sedation, an adult should take the initial dose of 0.1 mg to 0.2 mg IV at 2 to 3-minutes intervals to the desired degree of reversal.
If opioids are not present, Naloxone has little to no effect. If opioids are present, the side effects might be sweating, nausea, restlessness, trembling, vomiting, flushing, and headache, and has in rare cases, been associated with heart rhythm changes, seizures, and pulmonary edema.
The Cost of Naloxone
An online search for the wholesale price for sale of Naloxone for distributors will reveal a wide range of costs. It will vary from store to store depending on your visit and the country of the wholesale market.
As Naloxone is a globally found drug, its prices can fluctuate depending on the country. in the UK, in 2018, Naloxone costs the NHS about £5 per dose. In Australia, Naloxone with prescription is less expensive than without it, for a single dose without prescription Naloxone costs about AU$20, and for five doses with a prescription, Naloxone costs about AU$40. In the US, a 0.4 mg/ml vial of Naloxone costs about $7.07 per ml, a 0.4 mg/ml ampul of Naloxone costs about $4.78 per ml. Under the final dosage form of injectable solutions of 0.4 mg/ml, Naloxone costs from $4.07 to $13.92 per ml.
As Naloxone is available globally, fraudulent online websites may attempt to sell an illegal generic version of Naloxone. Thanks to Pipelinepharma online marketplace, you can be sure of the qualifications of the Naloxone sellers because they all have been through quality control procedures. Plus, being sure your future partner is qualified, you will save time sourcing for the product and buyer, because it is all in one safe place: Pipelinepharma B2B marketplace. On the intuitive platform, you can easily place orders or inquiries for any pharmaceutical products, including Naloxone. From our online marketplace, Naloxone is mostly available from the US, Australia, the EU, Argentina, India, South Korea, Vietnam, and Switzerland.
Navigating our Pharmaceutical Marketplace
Being a global B2B pharmaceutical online marketplace, Pipelinepharma is structured to simplify pharmaceutical deals by providing you with an intuitive interface that is easy to engage with. The selection of Naloxone distributors offerings can be narrowed down with the use of filters and easily weighed against one another according to medication prices and commercial terms. The advanced filters help you filter out the countries for these substance manufacturers and this substance Naloxone suppliers that you are looking for. These also enable you to check the dossier status of this medicine and the GMP approvals of the different variants of Naloxone. Also, each manufacturer or supplier product description contains essential information about this substance including clinical data, stability zones, countries where Naloxone is already registered in. Manufacturers also have special, and delivery terms.
Establishing Commercial Ties
If you are a pharmaceutical licensing company or a distributor you can enter into deals or negotiations over these medicine offers with manufacturing companies after completing the free registration process and joining our online marketplace. This helps to ensure that you conclude the pharmaceutical product deal at a reasonable cost and achieve the best cost/benefit ratio for your company while bypassing lengthy sourcing, negotiation, and order process. Once you have finalized a deal, you can look forward to a long-lasting business relationship with the manufacturer's Naloxone suppliers. This way, the marketplace allows you as a distributor to skip the process of shortlisting product manufacturers every time you are looking for in-licensing or distribution deals.
To keep up to the quality standards other than Good Manufacturing Practice approvals that this medicine manufacturers list has, we qualify their companies before they are onboarded on the platform. This allows us to screen Naloxone Manufacturers for the quality of the pharmaceutical products’ dossiers and protect against the risk of possible malpractices.