MAXIFLOXACIN HYDROCHLORIDE
Moxifloxacin Hydrochloride is an antibiotic used to treat a number of bacterial infections
including respiratory tract infections-pneumonia, conjunctivitis, endocarditis, tuberculosis,
sinusitis, cellulitis, anthrax, intra-abdominal infections and meningitis. Its actions result in
bacterial death as it blocks their ability to duplicate their DNA.
Moxifloxacin Hydrochloride is used in several medical preparations and is thus sold under
several brand names like Avelox, Avelox I.V. to name a few.
Bayer Aktiengesellschaft started filing the first patents in 1990s. It was patented in 1988 and
approved for use in the U.S. in 1999. Due to its efficacy, safety and use around the world, the
World Health Organization's has put Moxifloxacin Hydrochloride on the list of Essential and safe
needed in a health system.
Forms with dosage:
Moxifloxacin Hydrochloride is available in tablets. A general dose is last between 3 and 15 days
with a 400mg tablet. In initial recommended adult dose for the treatment of sinus and lung
infections is one 400-mg tablet taken once per day. For treating community-acquired
pneumonia, the initial dose starts at One 400-mg tablet taken once per day and so is the
dosage for Skin infections and plague.
The price of Moxifloxacin Hydrochloride
In the USA, the consumer has to pay an average retail price of $121.14 for 1 eye dropper of 3ml
with 0,5% concentration of Moxifloxacin Hydrochloride. The price of 5 tablets of 400 mg costs
USD17. The price of this medicine is cheaper in the developing world. In India, a supply of 5
tablets of 400 mg cost US$1.75
How does Moxifloxacin Hydrochloride work?
Moxifloxacin is a broad-spectrum antibiotic. It is active against both Gram-positive and Gram-
negative bacteria. It actions inhibiting DNA gyrase, a type II topoisomerase, and topoisomerase
IV, enzymes necessary to separate bacterial DNA. The final result of this inhibition is that it
stops cell replications.
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