What is the Irinotecan drug?
Irinotecan is an antineoplastic enzyme inhibitor; it reduces the spread of the cancer cells in the body. It is a medication used to treat colon cancer and small cell lung cancer. Irinotecan is usually administered during chemotherapy as a single agent or in combination with other drugs.
The FDA, in the US, approved the medical use of Irinotecan medication in 1996. Irinotecan is on the WHO's List of Essential Medicines, the safest and most effective medicines needed in a health system. The natural compound camptothecin found in the Chineses ornamental tree Camptotheca acuminata is used to make the Irinotecan medication.
Irinotecan manufacturers and wholesalers:
The US brand name for Irinotecan is Camptosar. Irinotecan is a globally found drug. Among all the manufacturers, we can list some, such as Pfizer Inc, Accord Healthcare Inc, Actavis Totowa Llc, Teva Parenteral Medicines Inc, and Watson Laboratories Inc.
Irinotecan suppliers market it in the forms of 20 mg solutions or solutions for injection.
Under the generic names, for injection of Irinotecan, the drug can be found at different dosages: 40 mg/2 ml; 100 mg/5 ml; 300 mg/15 ml; 500 mg/25 ml. For Camptosar, the solution for injection can be marketed in the strength of 40 mg/2 ml; 100 mg/5 ml; 300 mg/15 ml.
Irinotecan for sales:
On the US market, the price of Irinotecan can vary if it is sold under the generic name or the brand name. For 20mg/ml of an intravenous solution of Irinotecan, it can cost from $17 to $202 for 2ml, about $19.60 for 5ml, and about $131.30 for 25ml.
The prices for Irinotecan under the brand name Camptosar are slightly different. For Camptosar 20 mg/ml intravenous solution, 2 ml costs about $35.60, 5 ml about $48.48, and for 15ml, it costs about $126.43
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How to use Irinotecan drugs?
Using Irinotecan medication as a single agent for the treatment of colorectal cancer, an adult should be administered 125 mg/m2 IV over 90 minutes on Days 1, 8, 15, and 22 then 2-week rest or 350 mg/m2 IV over 90 minutes on Day 1 every three weeks.
Taking Irinotecan can cause some side effects, the most common ones are severe diarrhea, black, tarry stools, blood in the urine or stools, blurred vision, changes in skin color, and chest pain or discomfort.