Glibenclamide:
Glibenclamide, or also known as glyburide, is a drug used for the effective treatment of type 2 diabetes. It was developed in the 1960s during a cooperative study between the two companies Boehringer Mannheim (now Roche) and Hoechst (now Sanofi-Aventis). Following appraisal, it was approved for medical use in the United States in 1984. Glibenclamide can now be distributed in a cost effective manner as a generic medication in line with other pharmaceutical products which have had their patent expire. As such, it is offered for both sale and wholesale at various price points and under different brand names, including Gliben-J, Daonil, Diabeta, Euglucon, Gilemal, Glidanil, Glybovin, Glynase, Maninil, Micronase and Semi-Daonil. Additionally, glibenclamide manufacturers commonly list it as a combination drug with metformin. Which is sold under brand names, including Bagomet Plus, Benimet, Glibomet, Gluconorm, Glucored, Glucovance, Metglib, and others.
Method of action of glibenclamide:
Glibenclamide belongs to a group of drugs called sulfonylureas which treat type 2 diabetes by augmenting the secretion of insulin in pancreatic beta cells. This is facilitated by the inhibition of regulatory subunits causing cell membrane depolarization, allowing calcium access intracellularly and subsequent stimulation of insulin release. With insulin being the hormone responsible for the regulation of blood sugar by promoting the absorption of glucose from the blood into the liver, fat, and skeletal muscle cells. Conferring effective treatment of type 2 diabetes and associated symptoms such as excessive thirst, dysuria, and lethargies.
Glibenclamide containment and dosage:
Glibenclamide manufacturers and glibenclamide suppliers package the medication in tablet, capsule, or oral suspension form. With one 5mg tablet or capsule typically being prescribed to be taken once a day with breakfast or immediately after. This dose can be adjusted by a medical professional up to a recommended two 15mg doses twice a day. It is best taken alongside participation in exercise and at a consistent time. Liquid suspensions are predominantly used for the treatment of infants, with the dosage adjusted to match.
Glibenclamide on Pipelinepharma:
Due to the generic nature, there exists a wide variety of glibenclamide suppliers, distributors, and manufacturers on the market offering their product for wholesale. Searching on our company Pipelinepharma.com online marketplace currently reveals 28 verified global B2B providers located in countries, including India, Mexico, Turkey, the European Union, Israel, Ukraine, Brazil, Switzerland, Jordan, China, South Korea, Egypt, Argentina, Russian, Kuwait, and Oman. These are trusted manufacturers and distributors which have been verified according to strict quality control by the Pipelinepharma team.
Price of glibenclamide and how to buy:
As with other products, the cost of purchase remains confidential and negotiable online between both B2B parties. However, in certain cases, the manufacturer or wholesaler may have chosen to include a desired price to facilitate an order, if so, this indicated cost per sample will be visible in the Pipelinepharma.com list. As such, this enables a clear route for a buyer looking to source glibenclamide or any other pharmaceutical products from an array of global trusted manufacturers and distributors.