What is Fosfomycin?
Fosfomycin is an antibiotic that is used to treat bladder infections. It is marketed as 3mg oral powder. Manufacturing companies Merck & Co and Compañía Española de Penicilina y Antibióticos developed this drug. The drug is now approved in and distributed to numerous markets worldwide, including but not limited to China, Japan, Pakistan, the U.S., and Canada. This pharmaceutical remedy is also on the World Health Organisation's list of Essential Medicines that contains the safest and most effective drugs recommended for a health system. Currently, the drug is available as both generic and trade name medications. Monurol and Monuril produced by manufacturer Zambon and supplied by Allergan is the most popular brand name drug available. Other notable suppliers include Sanofi-Aventis, Sandoz, and Infectopharm. Buyers are advised that online sellers may attempt to market fraudulent versions of the generic drug, whereas Pipeline Pharma, through its pre-auditing and quality control procedures ensures that only verified manufacturers and wholesalers enter our online marketplace, offering you a risk-free B2B pharmaceutical sales platform.
Fosfomycin is prescribed for the treatment of simple cystitis caused by susceptible strains of E. coli and Enterococcus faecalis.
It is a medication with a low molecular weight that is hydrophilic. This pharmaceutical medicine is readily absorbed in the small intestine and broadly disseminated to the tissues when taken orally. The oral bioavailability ranges between 34 and 58 percent. Co-administration of this drug with meals reduces gastrointestinal absorption by about 30%.
The kidneys eliminate almost all of Fosfomycin. Factors such as meal administration decreased renal function, and advanced age may reduce the rate of its elimination.
It is typically administered in a single dose. Unless your doctor instructs you otherwise, do not take more than one dose at a time. This medication can be taken with or without food. It is a powder medicine that must be combined with water before use. Do not consume the dry powder without first diluting it with water. In 3 to 4 ounces (1/2 cup) cold water, dissolve the powder. Stir this concoction thoroughly and drink it all straight away.
Nausea, upset stomach, mild diarrhea; headache, dizziness; weakness; sore throat, runny nose; back pain; and vaginal itching or discharge are all common side effects associated with this pharmaceutical medicine.
Overdose has been associated with reduced hearing, vestibular loss, a general reduction in taste perception, and a metallic taste. In the event of an overdose, the patient should be treated symptomatically and supportively.
Antibiotics can cause diarrhea, which could be an indication of a new illness. Stop using this medicine if you experience watery or bloody diarrhea. Unless your doctor instructs you otherwise, do not take anti-diarrhea medication. This drug is categorized as pregnancy category B by the FDA. It is not predicted that it may harm an unborn child.
How does Fosfomycin work?
Fosfomycin kills bacteria by attaching covalently to a cysteine in the active site of the UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) enzyme, rendering it inert. It inhibits the formation of the peptidoglycan precursor UDP-N-acetylmuramic acid by blocking MurA from catalyzing the condensation of phosphoenolpyruvate (PEP) with UDP-N-acetylglucosamine (UNAG) (UDP-MurNAc).
The Wholesale Price of Fosfomycin
The wholesale acquisition cost of treatment with Fosfomycin powder in the U.S. is 95 USD. In the EU, the retail price per 3mg sachet of its powder is approximately 10-11 EUR.
Sourcing the Fosfomycin Manufacturers and Suppliers
Navigating our pharmaceutical marketplace
Being a global B2B pharmaceutical online marketplace, Pipelinepharma is structured to simplify pharmaceutical deals by providing you with an intuitive interface that is easy to engage with. The selection of Fosfomycin offerings can be narrowed down with the use of filters and easily weighed against one another according to medication prices and commercial terms. The advanced filters help you filter out the countries for this substance manufacturers and this substance suppliers that you are looking for. These also enable you to check the dossier status of this medicine, and the GMP approvals of the different variants of this pharmaceutical remedy. Also, each manufacturer or supplier product description contains essential information about this substance including clinical data, stability zones, countries where this drug is already registered in. Manufacturers also have special, and delivery terms.
Establishing commercial ties
If you are a pharmaceutical licensing company or a distributor you can enter into deals or negotiations over this medicine offer with manufacturing companies after completing the free registration process and joining our online marketplace. This helps to ensure that you conclude the pharmaceutical deal at a reasonable cost and achieve the best cost/benefit ratio for your company while bypassing lengthy sourcing, negotiation, and ordering process. Once you have finalized a deal, you can look forward to a long-lasting business relationship with the manufacturers or suppliers. This way, the marketplace allows you as a distributor to skip the process of shortlisting product manufacturers every time you are looking for in-licensing or distribution deals.
To keep up to the quality standards other than Good Manufacturing Practice approvals that this medicine manufacturers list has, we qualify their companies before they are boarded on the platform. This allows us to screen Fosfomycin manufacturers for the quality of the pharmaceutical products’ dossiers and protect against the risk of possible malpractices.