Markets of interest
As a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity, Flunarizine is used in the prophylaxis of migraine, occlusive peripheral vascular disease, the vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy. The medication inhibits the influx of extracellular calcium through myocardial and vascular membrane pores by physically plugging the channel. The decrease in intracellular calcium inhibits the contractile processes of smooth muscle cells, causing dilation of the coronary and systemic arteries, increased oxygen delivery to the myocardial tissue, decreased total peripheral resistance, decreased systemic blood pressure, and decreased afterload.
The drug is available for sale in the form of tablets at concentration 10 mg, and capsules at concentrations 5mg and 10 mg, from manufacturers in various countries including Y. The drug is provided by a wide range of Flunarizine suppliers from various countries including the Y, Y, and Y. Mostly due to the availability of raw materials for the manufacturing process and low labor costs, the leading Flunarizine manufacturers and distributors are based in China and India.
Licensing and brand names
Flunarizine was approved for commercial use under the brand name Orphan in the European Union by EMA in 2013. The medication is presently approved in many countries and is available in both generic and trade name versions. Flunarizine is not FDA approved in the USA, in part, due to its tendency to induce parkinsonism.
The medication is marketed under the trade names including Sibelius, Orphan, Zinasen, Gradient, Fluxarten and Funeral. One of the most popular branded versions of Flunarizine is manufactured and supplied by the Chinese pharmaceutical company Shandong Octagon Chemicals Limited. Other manufacturing companies and distributors from the European Union and India, have also successfully adapted to the demands of the global marketplace and produce a variant of the drug with Flunarizine as an active ingredient.
Target supply price
The wholesale acquisition cost of medication in the EU of this drug depending on the pack size ranges between 30 EUR and 100 EUR. The medication wholesale prices and commercial terms can vary depending on the supplier.
Information from manufacturers
We provide a detailed list of the Flunarizine manufacturers and suppliers that you are looking for. You can also find the dossier status of Flunarizine and the GMP approvals of the different variants of the medication. The product description of all Flunarizine suppliers contains essential information about the medication you order including clinical data, stability zones, and a list of countries where Flunarizine is already registered in. Manufacturers also specify the commercial terms of their offers, such as the market for which the offer is intended, deal type, dossier licensing fee, supply price, payment terms as well as delivery terms. Buyers are advised that online sellers may attempt to market fraudulent versions of the generic drug, whereas Pipeline Pharma, through its pre-auditing and quality control procedures ensures that only verified Flunarizine suppliers and distributors enter our online marketplace, offering you a risk-free global B2B pharmaceutical sales platform.