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Everolimus manufacturers

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Country of origin : Greece

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everolimus

Tablets 2.5 mg, 5 mg, 10 mg

Dossier type
EU CTD
Dossier status
Ready to file
Country of origin
European Union
GMP approvals
EU GMP
Manufacturer #260
Pharmaceutical manufacturer operating in the EU for 50+ years. Activities include scientific development, manufacturing, out-licensing, marketing, and distribution of high-quality generic medicines. The company owns several production facilities that all comply with EU GMP requirements. Key dosage forms include conventional solids, cytostatic injectables, and cytostatic orals. The company holds an in-house R&D and Intellectual property business unit, as well as a regulatory affairs team that prepares CTD dossiers and maintains direct contact with regulatory agencies worldwide. The portfolio includes more than three thousand MA sets approved in the EU while hundreds of MA are in progress. Key therapy lines are cardiovascular, CNS, diabetes, immunology, oncology, and more. The company is active in nearly 100 countries worldwide, selling its products in Africa, Asia, Australia, Europe, LATAM, and the Middle East.

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Everolimus Manufacturers

Everolimus belongs to the group of drugs known as kinase inhibitors. Everolimus cures cancer by preventing cancer cells from procreating and by reducing their blood supply. Everolimus reduces immune system activity to prevent transplant rejection. A specific type of pancreatic, stomach, intestines, or lung cancer that has spread or advanced and cannot be surgically treated is also treated with everolimus (Afinitor). Patients with tuberous sclerosis complex may also receive treatment with everolimus (Afinitor) for kidney cancers (TSC; a genetic condition that causes tumours to grow in many organs). Everolimus (Afinitor and Afinitor Disperz) is also used to treat TSC in adults and children 1 year of age and older who have subependymal giant cell astrocytoma (SEGA), a kind of brain tumour. Everolimus (Afinitor Disperz) is also used to treat specific types of seizures in adults and children with TSC 2 years of age and older when combined with other drugs. Everolimus is a drug that is used to treat advanced renal cell carcinoma (RCC; kidney cancer) after it has failed to respond to conventional treatments. This medicine is also used to cure a specific type of metastatic breast cancer which has already received at least one other treatment. Afinitor is a brand name for the generic medication. When referring to the generic medicine name everolimus, health care practitioners may use the brand name Afinitor. It is a chemotherapeutic medication, and referred to as a mTOR kinase inhibitor. Everolimus may have unwanted effects such as nausea, vomiting, diarrhoea, constipation, altered taste in food, weight loss, dry mouth, weakness, headache, trouble falling or staying asleep, nosebleed, dry skin, acne, problems with the nails, hair loss, pain in the arms, legs, back, or joints, muscle cramps, missed or irregular periods, heavy menstrual bleeding, difficulty getting or maintaining an erection, anxiety, aggression, or other behavioural changes.

How does Everolimus work?

Everolimus is a blocker that binds to the FK506 binding protein-12 with such a high affinity, producing a pharmacological complex that suppresses mTOR activity. This inhibition decreases the action of downstream effectors, preventing cells from progressing from G1 to S phase and, as a result, causing cell growth arrest as well as apoptosis. It also reduces the expression of vascular endothelial growth factor via inhibiting the expression of hypoxia-inducible factor. Cell proliferation, angiogenesis, and glucose absorption are all reduced when mTOR is inhibited by It. This medicine can be taken as a tablet. It is commonly taken once a day to treat kidney tumours and seizures in persons with TSC, RCC, or breast, pancreas, stomach, intestinal, or lung cancer. It is commonly used twice a day in conjunction with cyclosporine to avoid transplant rejection.

The Cost of Everolimus

An online search for the wholesale price for sale of Everolimus for distributors will reveal a wide range of costs. It will vary from store to store depending on your visit and the country of the wholesale market. Depending on the drugstore you visit, everolimus oral tablet 2.5 mg costs roughly $11,349 for a supply of 28 tablets. Pharmaceutical corporations generally support patient assistance programmes (PAPs), which provide free or subsidised drugs to low-income, uninsured, or under-insured people who meet certain criteria.

Navigating our pharmaceutical marketplace

Being a global B2B pharmaceutical online marketplace, Pipelinepharma is structured to simplify pharmaceutical deals by providing you with an intuitive interface that is easy to engage with. The selection of Everolimus distributors offerings can be narrowed down with the use of filters and easily weighed against one another according to medication prices and commercial terms. The advanced filters help you filter out the countries for these substance manufacturers and this substance Everolimus suppliers that you are looking for. These also enable you to check the dossier status of this medicine and the GMP approvals of the different variants of Everolimus. Also, each manufacturer or supplier product description contains essential information about this substance including clinical data, stability zones, countries where Everolimus is already registered in. Manufacturers also have special, and delivery terms.

Establishing commercial ties

If you are a pharmaceutical licensing company or a distributor you can enter into deals or negotiations over these medicine offers with manufacturing companies after completing the free registration process and joining our online marketplace. This helps to ensure that you conclude the pharmaceutical product deal at a reasonable cost and achieve the best cost/benefit ratio for your company while bypassing lengthy sourcing, negotiation, and order process. Once you have finalized a deal, you can look forward to a long-lasting business relationship with the manufacturers Everolimus suppliers. This way, the marketplace allows you as a distributor to skip the process of shortlisting product manufacturers every time you are looking for in-licensing or distribution deals.

Quality Assurance

To keep up to the quality standards other than Good Manufacturing Practice approvals that this medicine manufacturers list has, we qualify their companies before they are onboarded on the platform. This allows us to screen Everolimus Manufacturers for the quality of the pharmaceutical products’ dossiers and protect against the risk of possible malpractices.