Emoxypine

Emoxypine or ethylmethylhydroxypyridine succinate is a 3-hydroxy pyridine derivative that is quite similar in structure to Vitamin B6 or pyridoxine. Emoxypines most important components of the mechanism of action are their antioxidant and membranotropic effects. It has the ability to modulate receptors and membrane-bound enzymes function and restores a neurotransmitter balance. Due to its mechanism of action, it has at least two levels of pharmacological effects, neuronal and vascular. Emoxypine is neuroprotective, nootropic, anti-stress, anxiolytic, anticonvulsant, anti-alcohol, antihypoxic, anti-ischemic, heterotrophic, cardioprotective, anti-atherogenic, neuroprotective amongst other properties. It improves cerebral circulation and microcirculation. It also inhibits thrombocyte aggregation, while lowering cholesterol levels, and has cardio-protective and anti-atherosclerotic properties. Emoxypine is distributed in Russia but it is widely unknown around the world. In Russia, emoxypine has a wide range of applications including anxiolytic, anti-stress, anti-alcohol, anticonvulsant, nootropic, neuroprotective and anti-inflammatory action. Emoxypine is sold as Mexidol or Mexifin in succinate salt form. Pharmasoft Pharmaceuticals in Russia manufacture Emoxypine. As a Russian company, they did not file for licenses in the United States or Europe. L.D. Smirnov and K.M. Dumayev.

Dosage and administration

Emoxypine is available as tablets and pills. The recommended initial adult dose is 125-250 mg or 1-2 pills, taken 1-2 times a day. This is then gradually increased till the desired therapeutic effect is obtained while not exceeding 800 mg or 6 pills a day. This dosage varies as doctor's severity of the condition and the disease.

The cost of Emoxypine

In the global market, consumers have to pay USD 28 for 50 tablets of 125mg strength.

How does Emoxypine Work?

Emoxypine's has similar actions to antioxidant and membrane-protective effects. However, it is marked with key components, where it inhibits free radical oxidation of biomembrane lipids. It also reacts to peroxide radicals of lipids primary and hydroxyl radical of peptides, increasing the antioxidant enzyme activity, specifically superoxide dismutase. superoxide dismutase is responsible for the formation and consumption of lipid peroxides and active oxygen forms. Emoxypine's inhibits free radicals during the synthesis of prostaglandin catalyzed cyclooxygenase and lipoxygenase, thereby increasing the correlation between prostacyclin/ thromboxane A2 and blocks the leukotriene formation. In also increases the content of polar fraction of lipids and decreases cholesterol or phospholipids ratio proving its lipid-regulatory properties. It can also shift structure transition into the low-temperature zones provoking membrane viscosity reduction and the increase of its fluidity, eventually resulting in lipid-protein ratio improvement. It activity modulates membrane-bound enzymes, phosphodiesterase, cyclic nucleotides, adenylate cyclase, aldoreductase, acetylcholinesterase. Through this, it can modulate the receptor complexes of the brain membranes and increases their binding ability. It is also involved in stabilizing membrane structures of blood cells, called erythrocytes and thrombocytes during hemolysis or mechanical injury accompanied by free radicals formation.

Finding Emoxypine Manufacturers and Suppliers:

The process of finding trusted Emoxypine manufacturers and Emoxypine suppliers can be made quicker and more accessible by using Pipelinepharma's online platform, a B2B a marketplace that lets you finalize the deals of pharmaceutical products in a matter of a few clicks. Also, it is an easy to use online platform to grow your business opportunities. The robust search engine makes it convenient to search for manufacturers and suppliers of Emoxypine . The search can be further refined with industry-specific filters such as dossier type, country of origin, GMP approvals, and search criteria for Wholesaler, etc. helping to get in contact with the preferred manufacturer and supplier readily.