Doxylamine succinate is a medication belonging to a group of pharmaceutical products termed first-generation antihistamines. It is used to treat a variety of indications, most commonly as a short-term sedative and hypnotic. Doxylamine succinate manufacturers and doxylamine succinate suppliers also typically list it for sale in combination formulations with other drugs, this confers additional night-time allergy and cold relief. A common combination sold by distributors is preparations containing analgesics paracetamol (acetaminophen) and codeine, which aid in that calmative effect. It is also produced by manufacturers in combination with vitamin B6 (pyridoxine) to prevent morning sickness in pregnant women.
Currently, doxylamine succinate can be found on manufacturers and distributors pharmaceutical products wholesale list at a variety of price points. This is largely driven by doxylamine succinate’s wide regulatory acceptance and emerged generic nature, since its first discovery and patent in 1949. This has made it both attractive and cost-effective for suppliers to list in their global B2B drugs portfolio.
Method of action of Doxylamine succinate:
Doxylamine succinate is an antihistamine belonging to ethanolamine class, with powerful antihistamine and anti-allergy effects. It is one of the most powerful over the counter sedatives available for purchase in the United States and functions through its competitive action binding to the H1 receptor. This prevents histamine from binding, resulting in the sedative and anti-allergic effects. Doxylamine also acts as an antagonist of the muscarinic acetylcholine receptors, causing a series of downstream actions, which result in its minor hypnotic, anticholinergic, and (at high doses) deliriant effects.
Form and dosage of doxylamine succinate:
As with all drugs, the final form and packaging are dependent on the manufacturers and suppliers, as well as the distributor and specific order. However, doxylamine succinate typically comes in forms such as tablets, film-coated tablets, capsules, liquid capsules, oral solutions, chewable tablets, and prolonged-release tablets. It is an over the counter medication, as such it does not require a specific prescription for use. Normal doses vary based on the individual and the underlying indication. However, manufacturers recommend 25 mg orally once a day, 30 minutes before bed for the treatment of adults suffering from insomnia. For the adult treatment of allergies, a recommended dose is 50 mg orally every 4-6 hours as needed. Caution should be applied if continued use passes two weeks, if so, it would be prudent to bring this up with a professional healthcare provider.
Doxylamine succinate on Pipelinepharma:
Currently, we have found 4 trusted doxylamine succinate manufacturers and doxylamine succinate suppliers from our global list of online B2B sellers. These manufacturers and wholesale sellers are located in countries including the European Union, India, and Argentina. Every company on our online B2B marketplace has been verified by the Pipelinepharma team according to strict quality control. This ensures seller legitimacy and reduces sourcing mileage, facilitating a quick and pain-free transaction experience.
Price of doxylamine succinate and how to buy:
As with all pharmaceutical products, the cost of doxylamine succinate is highly dependent on numerous factors such as organisation, quantity, and location. However, a cursory search online reveals the typical cost for wholesale purchase is approximately in the range of USD 8 for 20 mg of Doxylamine Succinate. Although specific prices remain confidential between both B2B parties on the online Pipelinepharma marketplace, sellers may choose to list the desired price for their product to facilitate negotiations. If so, this will be indicated with an ‘Accept’ and ‘Negotiate’ button. In the absence of a listed price a ‘Get offer’ button will instead be displayed.