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28 products found

dobutamine

Vials, injection 50 mg/4 ml, 250 mg/20 ml

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
EU GMP, WHO
Manufacturer #2303

Manufacturer usually replies in 6 days

dobutamine

Vials, injection 50 mg/ml, 250mg/20ml - 20 ml, 5 ml

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
EU GMP
Available for
Licensing with supply, Distribution only
Manufacturer #18885

Manufacturer usually replies in 7 days

dobutamine

Injection 50 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Manufacturer #19540

Manufacturer usually replies in 4 days

dobutamine

Vials 12.5 mg/ml - 5 ml

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
GMP, WHO
Manufacturer #24869

Manufacturer usually replies in 3 days

dobutamine

Injection 250 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Manufacturer #20401

Manufacturer usually replies in 5 days

dobutamine

Injection 250 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Manufacturer #20159

Manufacturer usually replies in 10 days

dobutamine

Injection, pre-filled syringe 50 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Manufacturer #20087

Manufacturer usually replies in 8 days

dobutamine

Injection 50 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Manufacturer #20087

Manufacturer usually replies in 8 days

dobutamine

Injection 50 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Manufacturer #20368

Manufacturer usually replies in 8 days

dobutamine

Injection 250 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Manufacturer #19884

Manufacturer usually replies in 6 days

dobutamine

Ampoules, injection 250 mg/5 ml

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO, INVIMA
Manufacturer #18529

Manufacturer usually replies in 8 days

dobutamine

Injection 50mg/ml, 12.5mg/ml

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Available for
Licensing with supply
Manufacturer #10323

Manufacturer usually replies in 5 days

dobutamine

Injection 50 mg / ml, 250 mg / 20 ml

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Manufacturer #18204

Manufacturer usually replies in 9 days

dobutamine

Injection 250 mg / 5 ml

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Manufacturer #17417

Manufacturer usually replies in 6 days

dobutamine

Vials, lyophilized injection 250 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Manufacturer #17417

Manufacturer usually replies in 6 days

dobutamine

Solution for injection/infusion 250mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Manufacturer #17147

Manufacturer usually replies in 7 days

dobutamine

Injection 250 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Manufacturer #20801

Manufacturer usually replies in 11 days

dobutamine

Powder for solution for injection/infusion 250 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Manufacturer #20158

Manufacturer usually replies in 11 days

dobutamine

Ampoules, injection 50 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Manufacturer #19707

Manufacturer usually replies in 11 days

dobutamine

Injection 50 MG

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Manufacturer #19051

Manufacturer usually replies in 14 days

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Dobutamine

Dobutamine is used to treat cardiogenic shock and severe heart failure and in certain types of cardiac stress tests. Dobutamine is more effective in the treatment of acute but potentially reversible heart failure, which may occur during cardiac surgery or in cases of septic or cardiogenic shock. Dobutamine can also be used in congestive heart failure to improve cardiac output. Dobutamine is specifically for parenteral therapy when it is necessary for inotropic support in the short-term treatment of cardiac decompensation resulting from depressed contractility. This depressed contractility is caused by organic heart disease or surgical cardiac procedures. However, it is not useful in treating ischemic heart disease. It improves heart rate, eventually resulting in the improvement of myocardial oxygen demand. It is also used in hospitals as a pharmacologic stress testing agent in the identification of coronary artery disease. Dobutamine is sold under the brand names like Dobutrex and Inotrex amongst others Eli Lilly scientists, Drs. Ronald Tuttle and Jack Mills, first developed it in the 1970s, as a structural analog of isoprenaline. Dobutamine received FDA approval for medical use in the United States in 1978. It is a generic medication and made from isoproterenol.

Dosage and administration

Dobutamine is available as an injection of 12.5 mg/mL. Each 20 mL Single-Dose Vials has 250 mg of dobutamine hydrochloride or 40 mL Single-Dose Vials which have 500 mg of Dobutamine hydrochloride. It is injected into the vein as a continuous infusion and the amount of medication needed is adjusted for the desired effect. It acts quickly and the onset of action can be felt within 2 minutes. For preparing the injection, Dilute the 20 mL vial in an IV container in at least 50 mL of diluent and dilute 40 mL in at least 100 mL of diluent. The intravenous solutions are diluted with Dextrose Injection 5%, Dextrose 5%, and Sodium Chloride 0.9% Injection, Dextrose Injection 10%, Lactated Ringer's Injection, 5% Dextrose in Lactated Ringer's Injection, in Water for Injection. The infusion of dosage recommended for cardiac output improvement is between 2.5 to 15 mcg per kilo per minute. This can be raised to 40mcg is the desired effect is not achieved at the regular dose.

The cost of Dobutamine

In the UAS, the consumer pay around $92 for a supply of 3000 milliliters of Dobutamine intravenous solution 1 mg/mL-D5%. This medicine is more affordable in the developing world. In India, the consumer pay around $2 for a supply of 5 vials of 5ml totaling 250mg milliliters of Dobutamine intravenous solution 1 mg/mL-D5%.

How does Dobutamine Work?

Dobutamine is a direct-acting inotropic agent. Its primary actions caused by stimulating beta- adrenoceptors in the heart where it creates relatively mild chronotropic, hypertensive, arrhythmogenic, and vasodilative effects. Dobutamine targets beta-1 adrenergic receptors while having negligible effects on beta-2 receptors. Unlike dopamine, It does not release endogenous norepinephrine. Dobutamine actions by stimulating the beta-1 receptors, increase myocardial contractility, and stroke volume. The final result is an increased cardiac output.

Finding Dobutamine Manufacturers and Suppliers:

The process of finding trusted Dobutamine manufacturers and Dobutamine suppliers can be made quicker and more accessible by using Pipelinepharma's online platform, a B2B a marketplace that lets you finalize the deals of pharmaceutical products in a matter of a few clicks. Also, it is easy to use an online platform to grow your business opportunities. The robust search engine makes it convenient to search for manufacturers and suppliers of Dobutamine. The search can be further refined with industry-specific filters such as dossier type, country of origin, GMP approvals, and search criteria for Wholesaler, etc. helping to get in contact with the preferred manufacturer and supplier readily.