Dirithromycin is an antibiotic that is used to treat a variety of infections, including those of the respiratory system, skin, and other organs. Dirithromycinit is a medication of macrolide glycopeptide antibacterial agent which is used to treat viral infections, pneumonia, tonsillitis, and skin problems, among other bacterial infections.
Mild-to-moderate infections caused by susceptible microorganisms include acute bacterial exacerbations of chronic bronchitis, a supplementary bacterial infection of acute bronchitis, community-acquired pneumonia, pharyngitis/tonsilitis, and uncomplicated skin and skin phase includes.
Oral dirithromycin is quickly absorbed, with an absolute bioavailability of around 10%.
Nausea, vomiting, epigastric distress, and diarrhea are some of the toxic symptoms that can occur after a macrolide antibiotic overdose.
During absorption, nonenzymatic hydrolysis converts dirithromycin to the active compound, erythromycylamine. Within 35 minutes of dosing, 60 to 90% of a dose is hydrolyzed to erythromycylamine, and conversion is nearly complete after 1.5 hours. Hepatic biotransformation of erythromycylamine is minimal. There were no other metabolites of dirithromycin found in the serum.
How does Dirithromycin work?
By interfering with bacteria's protein synthesis, dirithromycin prevents them from growing. Dirithromycin inhibits peptide translocation by binding to the 50S subunit of the 70S bacterial ribosome. Dirithromycin binds to the subunit 50S with a tenfold higher affinity than erythromycin. Furthermore, dirithromycin binds to two domains of 23S RNA of the ribosomal subunit 50S simultaneously, whereas older macrolides only bind to one. Dirithromycin can also stop ribosomal subunits the 50S and 30S from forming.
The Cost of Terizidone
An online search for the wholesale price for the sale of Dirithromycin for distributors will reveal a wide range of costs. It will vary from store to store depending on your visit and the country of the wholesale market.
Navigating our pharmaceutical marketplace
Being a global B2B pharmaceutical online marketplace, Pipelinepharma is structured to simplify pharmaceutical deals by providing you with an intuitive interface that is easy to engage with. The selection of Dirithromycin distributor’s offerings can be narrowed down with the use of filters and easily weighed against one another according to medication prices and commercial terms. The advanced filters help you filter out the countries for these substance manufacturers and this substance Dirithromycin suppliers that you are looking for. These also enable you to check the dossier status ofthis medicine and the GMP approvals of the different variants of Dirithromycin. Also, each manufacturer or supplier product description contains essential information about this substance including clinical data, stability zones, countries where Dirithromycin is already registered in. Manufacturers also have special, and delivery terms.
Establishing commercial ties
If you are a pharmaceutical licensing company or a distributor you can enter into deals or negotiations over these medicine offers with manufacturing companies after completing the free registration process and joining our online marketplace. This helps to ensure that you conclude the pharmaceutical product deal at a reasonable cost and achieve the best cost/benefit ratio for your company while bypassing lengthy sourcing, negotiation, and order process. Once you have finalized a deal, you can look forward to a long-lasting business relationship with the manufacturers or Dirithromycin suppliers. This way, the marketplace allows you as a distributor to skip the process of shortlisting product manufacturers every time you are looking for in-licensing or distribution deals.
To keep up to the quality standards other than Good Manufacturing Practice approvals that this medicine manufacturers list has, we qualify their companies before they are onboarded on the platform. This allows us to screen Dirithromycin Manufacturers for the quality of the pharmaceutical products’ dossiers and protect against the risk of possible malpractices.