Cinnarizine

Cinnarizine treats nausea and vomiting due to motion sickness, chemotherapy, vertigo, or Ménière's disease and Cogan's syndrome. An antihistamine is also a calcium channel blocker of the diphenylmethylpiperazine group. It has the rare distinction of having beneficial effect in the chronic treatment of the vertigo and tinnitus, associated with Meniere's disease. However, this medication causes drowsiness caused and is thus not or used very rarely amongst pilots and aircrew who must be dependably alert. British Royal Navy cited it as one of the most used drugs for seasickness. Cinnarizine is sold under the brand names such as Neurozine, Sezin and stugeron among others. Janssen Pharmaceutica first synthesized it in 1955. Cinnarizine, the nonproprietary name was given after the cinnamyl substituent on one of the nitrogen atoms. It combines with generic ending "-rizine" for antihistaminics or cerebral vasodilators. Cinnarizine is not available in the United States or Canada. However, it is sold in the EU and the rest of the world.

Dosage and administration

Cinnarizine is available as tablets of 15mg strength. While treating travel sickness, Adults and children aged 12 years or older are recommended to take two tablets two hours before travel, followed by one tablet every 8 hours during the journey, when needed. The dose for Children aged 5 to 11 years is one tablet, taken 2 hours before travel, followed by half a tablet every 8 hours during the journey when needed. When treating dizziness and sickness caused by inner ear problems, Adults and children aged 12 years or older are given two tablets to be taken 3 times a day and in Children aged 5 to 11 years, the dose is one tablet, taken 3 times a day.

The cost of Cinnarizine

In India, the consumers have pay a average retail price of USD1.5 for 25 tablets of to 25mg strength. This medicine is not sold in the US and Canada.

How does Cinnarizine Work?

Cinnarizine actions disrupt signal transmission between vestibular apparatus of the inner ear and hypothalamus, where the vomiting center in the brain resides. It does this by limiting the activity of the vestibular hair cells which send signals about movement. It is generally understood that, Vomiting in motion sickness is a compensatory mechanism of the brain, expressed physiologically. The confusion in brain whether the individual is moving or standing is reduced by abolishing the disparity of signal processing between inner ear motion receptors and the visual senses.

Finding Cinnarizine Manufacturers and Suppliers:

The process of finding trusted Cinnarizine manufacturers and Cinnarizine suppliers can be made quicker and more accessible by using Pipelinepharma's online platform, a B2B marketplace that lets you finalize the deals of pharmaceutical products in a matter of a few clicks. Also, it is an easy to use online platform to grow your business opportunities. The robust search engine makes it convenient to search for manufacturers and suppliers of Cinnarizine. The search can be further refined with industry-specific filters such as dossier type, country of origin, GMP approvals, and search criteria for Wholesaler, etc. helping to get in contact with the preferred manufacturer and supplier readily.