What is DEXMEDETOMIDINE HYDROCHLORIDE?
Dexmedetomidine is a pharmaceutical substance that is sold under the trade name Precedex amongst others, is an anxiety-reducing, sedative, and pain medicine. This pharmaceutical drug is well-known for its capacity to provide sedation outdoors risk of respiratory depression (unlike other generally used drugs such as propofol and fentanyl) and can provide usefulness or semi-rousable sedation.
Similar to clonidine, it is a sympatholytic drug that acts as an agonist of α2-adrenergic receptors insecure parts of the cerebrum. Veterinarians use dexmedetomidine for comparable purposes in treating kittens, dogs, and horses. It was revealed by Orion Pharma.
Dexmedetomidine is everywhere frequently practiced in the intensive care setting for light to modest sedation. It is not approved for long-term heartfelt sedation. A biography of dexmedetomidine is that it has analgesic characteristics in addition to its capacity as an anesthetic, but is opioid-sparing; thus, it is not associated with significant respiratory difficulty(unlike propofol).
Many studies recommend dexmedetomidine for sedation in mechanically ventilated adults may reduce the time to extubation and ICU sojourn. Characters on dexmedetomidine can be rousable and cooperative, an advantage in some schemes.
Compared amidst other sedatives, some considerations suggest dexmedetomidine may be associated with less delirium. Nevertheless, this finding is not compatible across multiple schoolrooms. At the very least, when aggregating many study decisions together, the use of dexmedetomidine resembles to be associated with less neurocognitive dysfunction examined to other sedatives. Whether this observation has a beneficial psychological impact is unclear. From an economic perspective, this pharmaceutical medicine is associated with lower ICU costs, mainly due to a more diminutive time to extubation.
Intravenous immersion of dexmedetomidine is commonly initiated with a loading dose followed by a continuance infusion. There may be great individual variability in the hemodynamic effects (especially on heart rate and blood pressure), as well as the sedative effects of this drug. For this reason, the dose must be carefully adjusted to achieve the desired clinical effect.
There is no absolute contraindication to the use of dexmedetomidine. It has a biphasic effect on blood pressure with lower sections at lower drug combinations and higher readings at higher intensities. Rapid IV administration or bolus has been associated with hypertension due to peripheral α2-receptor stimulation. Bradycardia can be a limiting factor with infusions, especially in higher doses.
How does it DEXMEDETOMIDINE HYDROCHLORIDE work?
Similar to clonidine, it is a sympatholytic medication that functions as an agonist of α2-adrenergic receptors in particular parts of the brain. Veterinarians use dexmedetomidine for similar purposes in treating cats, dogs, and horses.
The Wholesale Price of DEXMEDETOMIDINE HYDROCHLORIDE
The cost for dexmedetomidine intravenous solution (4 mcg/mL-NaCl 0.9%) is around $228 for a supply of 200 milliliters, depending on the pharmacy you visit.
Sourcing DEXMEDETOMIDINE HYDROCHLORIDE
Manufacturers and Suppliers
PipelinePharma has found 7 verified dexmedetomidine hydrochloride manufacturers and dexmedetomidine hydrochloride suppliers from our global list of sellers. The pharmaceutical drug is available for sale in various forms such as injection, solution for injection, vials, ampoules from manufacturers in various countries including China, India, Turkey.
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