What is the Darunavir drug?
Darunavir is a protease inhibitor; Darunavir is also an antiretroviral medication used to treat and prevent HIV/AIDS. Darunavir can act as a prevention for potential exposure to HIV, such as needlestick injury.
Tibotec developed Darunavir. The US approved the medical use of Darunavir in 2006, and the FDA approved Darunavir in 2008 for people not previously treated for HIV.
The Darunavir medication is on the WHO’s List of Essential Medicines.
Darunavir is also being studied as a possible treatment for SARS-CoV-2, the coronavirus responsible for COVID-19.
Darunavir manufacturers and wholesalers:
One of Darunavir brand name is Prezista in the US. Darunavir is a globally found drug.
One of the leading Darunavir manufacturers is Johnson & Johnson.
Darunavir suppliers market it in the form of oral film-coated tablets of 75 mg, 150 mg, 300 mg, 400 mg, 600 mg, and 800 mg. Darunavir can also be found in the final dosage form of an oral suspension of 100 mg/1 ml.
Darunavir for sales:
In the US, the Darunavir wholesale cost is more than $200 per month. Under the brand name Prezista, Darunavir costs change depending on the strength of its final dosage form. For an 800 mg tablet, Prezista costs about $61.76. For a 600 mg tablet, it costs from $25.75 to $30.88, for a 400 mg tablet, it costs about $18.74, for a 300 mg tablet about $16.2, for a 150 mg from $4.59 to $7.72, and for a 75 mg tablet, it costs from $2.3 to $3.86. For a 100 mg/ml oral suspension, Prezista costs about $5.17 per ml.
In the developing world, Darunavir costs about US$66 per month.
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How to use Darunavir drugs?
Darunavir is mostly taken alongside with other drugs, such as Ritonavir.
Darunavir helps to treat and prevent HIV infection, but it is not a cure. Darunavir should be taken with food; it increases the absorption.
There are two types of patients in the treatment of HIV: therapy-naive patient and therapy-experienced patient.
To treat HIV with Darunavir, if both types of patients have demonstrated no resistance to the substance, an adult should take 800 mg of Darunavir plus 100 mg of Ritonavir once a day. On the contrary, if therapy-experiences patients with at least one Darunavir Resistance-Associated Substitution or with No Baseline Resistance Information, an adult should take 600 mg of Darunavir 600 mg plus 100 mg of Ritonavir 100 mg twice a day.
If a patient is pregnant, she should take 600 mg of Darunavir plus 100 mg Ritonavir twice a day.
Taking Darunavir may have some side effects that include blurred vision, dry mouth, flushed or dry skin, fruit-like breath odor, increased hunger.