CEFPROZIL
Cefprozil is used to treat bacterial infections, such as infection of the airway tubes leading to the lungs (bronchitis). It is also prescribed in the treatment of other infections of the skin, ears, sinuses, throat, and tonsils. Cefprozil is from a family of antibiotics medications called cephalosporins. This family of antibiotics works by stopping the growth of bacteria.
Cefprozil is sold under brand name Cefzil amongst others.
Bristol-Myers Company discovered Cefprozil in 1983 and filed for patent. Cefprozil was approved for medical use in 1992.
Forms and Dose:
Cefprozil is available as a tablet, a liquid suspension, and as an oral suspension to be reconstituted. This medicine is sold in strengths from 125 mg/5 mL to 250 mg/5 mL. The oral tablet is sold in 250 mg, 500 mg strengths.
The recommended usual Adult Dose for treating Bronchitis is 500 mg, taken orally, every 12 hours for 10 days. In the treatment of Cystitis, the usual adult dose is 500 mg, taken orally, every 24 hours for 3 to 7 days. The recommended usual adult dose for Otitis Media is 500 mg, taken orally, every 24 hours for 5 to 10 days. For curing Pneumonia, the Usual Adult Dose for Community-acquired pneumonia for nonhospitalized patients is 500 mg, taken orally, every 12 hours for 7 to 21 days.
The recommended usual adult dose for treating Pyelonephritis is 500 mg, taken orally, every 12 to 24 hours for 14 days and the dose for Sinusitis is 250 to 500 mg orally every 12 hours for 10 days. In the treatment of Skin or Soft Tissue Infection, the Usual Adult Dose is 250 to 500 mg, taken orally, every 12 hours for 10 days or 500 mg orally every 24 hours for 10 days. The Usual Adult Dose for Tonsillitis and Pharyngitis is 500 mg orally every 24 hours for 10 days and the for treating Upper Respiratory Tract Infection, the dose is 500 mg, taken orally every 12 to 24 hours for 10 to 14 days.
The Cost of Cefprozil:
In the USA, the consumer has to pay around $24 for a 125mg/5 ml Oral powder for a supply of 50 millilitres. The 250 mg oral tablets cost $ 7.50 for 50 tablets and the 500 mg oral tablet costs $321.51 for 50 tablets. However, the price is significantly cheaper in the developing world, with generic brands. In India, the consumer pay USD53 for a supply of 60 tablets of 500 mg.
How does Cefprozil work?
Cefprozil works by stopping bacteria growth. Its actions Inhibit bacterial cell wall synthesis by binding to one or more of the penicillin-binding proteins. This inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. The final result is inhibition of cell wall biosynthesis. This process ends with lysing due to ongoing activity of cell wall autolytic enzymes while cell wall assembly is arrested.
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