What is CEFIXIME TRIHYDRATE?
Cefixime is a pharmaceutical substance that is sold under the brand name Suprax among others. It is an antibiotic remedy employed to wield a number of bacterial infections. These infections include otitis media, strep throat, pneumonia, urinary tract infections, gonorrhea, and Lyme disease. For gonorrhea typically only one dose is required. In the United States, it is a second-line treatment to ceftriaxone for gonorrhea. It is taken by mouth.
There are many side effects. Such as Common side consequences include diarrhea, abdominal pain, and nausea. Serious side effects may include allergic reactions and Clostridium difficile diarrhea. It is not suggested in people with an antiquity of severe penicillin anaphylaxis. It resembles to be comparatively safe during germination. It is in the third-generation cephalosporin class of medications. It operates by meddling with the bacteria's cell wall appearing in its separation.
Cefixime was copyrighted in 1979 and accepted for medical use in the United States in 1989. It is on the World Health Organization's List of Essential Medicines. It is available as a nonexclusive prescription in the United States.
Cefixime treats infections of the:
Urinary region: Uncomplicated urinary stretch infections caused by receptive isolates of Escherichia coli and Proteus mirabilis.
Ear: Otitis media generated by Haemophilus influenza, Moraxella catarrhalis, and Streptococcus pyogenes.
Throat: Tonsillitis including pharyngitis induced by Streptococcus pyogenes.
Chest and lungs: Chronic bronchitis caused by Streptococcus pneumonia and Haemophilus influenza.
Cervix and urethra: Gonorrhea (cervical/urethral) prompted by susceptive isolates of Neisseria gonorrhoeae (penicillinase-and non-penicillinase-producing isolates).
It is further done to treat typhoid temperature.
Cefixime is a broad-spectrum cephalosporin antibiotic and is commonly used to treat bacterial infections of the ear, urinary tract, and upper respiratory tract. The following represents MIC susceptibility data for a few medically significant microorganisms:
Escherichia coli: 0.015 µg/mL – 4 µg/mL
Haemophilus influenzae: ≤0.004 µg/mL – >4 µg/mL
Proteus mirabilis: ≤0.008 µg/mL – 0.06 µg/mL
The bactericidal development of Cefixime is due to the inhibition of cell wall synthesis. It secures one of the penicillin-binding proteins(PBPs) which repress the final transpeptidation round of the peptidoglycan structure in the bacterial cell wall, thus inhibiting biosynthesis and capturing cell wall adjustment resulting in bacterial cell death.
Absorption Only 40–50% is understood from the GI tract (oral bioavailability). Absorption may be decreased when taken with food. The ordinary zenith concentration after a regime of oral suspension is approximately 25–50% greater than the peak concentration following oral tablet or capsules administration.
Distribution has high concentrations in bile and urine. It can cross the placenta and its protein binding capacity is 65%.
It is always better to perform relevant cultures and perceptivity studies to determine the causative body and its sensitivity to cefixime.
How does CEFIXIME TRIHYDRATE work?
This pharmaceutical drug is in a class of vaccinations called cephalosporin antibiotics. It works by killing bacteria. Antibiotics such as cefixime will not operate for colds, flu, or other viral diseases. Managing antibiotics when they have not wanted heightens your risk of growing a contagion later than the continuous antibiotic approach.
The Wholesale Price of CEFIXIME TRIHYDRATE
The wholesale price of this pharmaceutical substance almost costs (USD/kg) $140 on average. Prices may vary from stores to pharmacies you visit.
Sourcing CEFIXIME TRIHYDRATE Manufacturers and Suppliers
PipelinePharma has found 8 verified cefixime trihydrate manufacturers and suppliers from our global list of sellers. The pharmaceutical drug is available for marketing in different forms such as granules for oral solution, tablets, film-coated, oral powder, tablets, capsules, oral suspension, syrup from manufacturers in various countries including Turkey, Kosovo, India.
PipelinePharma is a global B2B pharmaceutical online marketplace, that is structured so as to explain pharmaceutical appointments by fitting you with an intuitive interface that is easy to engage with. The selection of cefixime trihydrate offerings can be narrowed down with the use of filters and easily weighed against one another according to medication prices and commercial courses.