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Bosentan manufacturers

34 products found

Filters

34 products found

bosentan

Tablets, film coated 62,5mg, 125mg

Dossier type
EU CTD
Dossier status
Ready to file
Country of origin
European Union
GMP approvals
EU GMP
Registered in
France
Manufacturer #370
A pharmaceutical manufacturer based in the EU that has been active in 100+ countries selling its products for 20+ years. Key production lines are Rx and OTC. Main therapeutic areas include oncology, urology, and antivirals. The company's production lines are GMP-compliant. The company possesses branches in the Middle East and Asia.

Manufacturer usually replies in 3 days

bosentan

Tablets 125mg

Dossier type
EU CTD
Dossier status
Ready to file
Country of origin
European Union
GMP approvals
EU GMP
Manufacturer #12574
It is a fully integrated pharmaceutical firm that conducts cutting-edge scientific research and manufactures cutting-edge medications. The corporation also markets its products effectively and professionally. Thousands of patients benefit from the medications, which help them live better and longer lives. They raise funding for research and development by selling our products and borrowing money from the stock market.

Manufacturer usually replies in 4 days

bosentan

Tablets, film coated 62.5 mg, 125 mg

Dossier type
EU CTD
Dossier status
Ready to file
Country of origin
European Union
GMP approvals
EU GMP
Manufacturer #419

Manufacturer usually replies in 2 days

bosentan

Tablets, film coated 62,5mg, 125mg

Dossier type
EU CTD
Dossier status
Ready to file
Country of origin
European Union
Manufacturer #554

Manufacturer usually replies in 3 days

bosentan

Tablets, film coated 62.5 mg, 125 mg

Dossier type
EU CTD
Dossier status
Ready to file
Country of origin
European Union
GMP approvals
EU GMP
Comments
Reference product: Tracleer
Manufacturer #10142
They have more than 40 generic drug products available for license to our global partners. The EU-CTD format is used for all product dossiers. All generic drug products are manufactured in the European Union (EU) and distributed globally to brand partners. Concentrate on delivering high-quality products on time and at a reasonable price.

Manufacturer usually replies in 9 days

bosentan

Tablets 62.5 mg , 125 mg

Dossier type
EU CTD
Dossier status
Ready to file
Country of origin
Canada
GMP approvals
EU GMP, Canada
Comments
Reference product : Tracleer (Actelion)
Manufacturer #278

The company has become a prominent partner of the pharmacy community in North America, with the fastest rising market share among generic leaders. It can provide best-in-class supply reliability thanks to production capacity. In more than 50 countries, it's available locally or through corporate partnerships. R&D expenditures range from $40 million to $50 million per year. They are dedicated to maintaining a customer satisfaction rate of over 95% by continuously enhancing supply chain efficiency.

Manufacturer usually replies in 7 days

bosentan

Tablets 62.5mg, 125mg

Dossier type
EU CTD
Dossier status
Ready to file
Country of origin
Turkey
GMP approvals
EU GMP
Unavailable markets
Albania
Manufacturer #281
It is a leading European pharmaceutical firm that strives to create a powerful global brand with innovative goods and services, as well as bold and pioneering activities, by working passionately to heal the lives they touch. The business was founded in the 1900s. In the interest of public health and the national economy, the firm launched the project to promote public awareness about the unintentional use of medications.

Manufacturer usually replies in 8 days

bosentan

Tablets 62.5/125mg

Dossier type
EU CTD
Dossier status
Ready to file
Country of origin
India
Manufacturer #8228

Manufacturer usually replies in 2 days

bosentan

Tablets, film coated 125 mg, 62.5 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
Vietnam
GMP approvals
WHO, EU GMP
Manufacturer #21022

Manufacturer usually replies in 8 days

bosentan

Tablets 62.5 mg , 125 mg

Dossier type
CTD
Dossier status
Under development
Country of origin
India
GMP approvals
EU GMP
Manufacturer #15176

Manufacturer usually replies in 5 days

bosentan

Tablets 125 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
Uruguay
GMP approvals
WHO
Manufacturer #21285
It is a pharmaceutical company with more than 90 years of leadership in Latin America's market, which researches, develops, produces, represents, and distributes effective, reliable, and accessible products in all therapeutic areas for health care.

Manufacturer usually replies in 2 days

bosentan

Tablets 125 mg, 62.5 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
Pakistan
GMP approvals
Sri Lanka, Afghanistan, Vietnam, Cambodia, Myanmar
Manufacturer #21102

Manufacturer usually replies in 5 days

bosentan

Tablets 62.5 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Manufacturer #19464

Manufacturer usually replies in 2 days

bosentan

Tablets 62.5 mg , 125 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
Argentina
GMP approvals
PICS
Registered in
Argentina
Available for
Licensing with supply, Distribution only
Manufacturer #15733
One of the leading manufacturers in cosmetic and medicinal products in the South American Continent. The company has been committed since 1990-is to developing and manufacturing high-quality products that allow healing and improve someone’s life. They are a major exporter of its therapies to different regions such as Latin America and Asia. Medicine is manufactured for pain, gastroenterology, hepatology, and cardiology.

Manufacturer usually replies in 17 days

bosentan

Tablets, film coated 62.5 mg, 125 mg

Dossier type
EU CTD
Dossier status
Ready to file
Country of origin
Turkey
GMP approvals
EU GMP
Unavailable markets
Iran
Available for
Licensing with supply
Comments
Indication: Hypertension (PAH); Status: MA granted
Manufacturer #385

A pharmaceutical manufacturer based in the EU that has been active in 60+ countries selling its products in Europe, North America, LATAM, MENA, Africa, and Asia for 60+ years. Key production lines are Rx and nutraceuticals. The company's production lines are EU GMP-compliant.

Manufacturer usually replies in 11 days

bosentan

Tablets 62.5 mg, 125 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
EU GMP, WHO
Manufacturer #2303

Manufacturer usually replies in 6 days

bosentan

Tablets for oral solution 62.5 mg, 125 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
Pakistan
GMP approvals
WHO
Manufacturer #19907

Manufacturer usually replies in 6 days

bosentan

Tablets 62.5 mg, 125 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Manufacturer #19670

Manufacturer usually replies in 8 days

bosentan

Tablets 62.5 mg, 125 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Manufacturer #17691

Manufacturer usually replies in 7 days

bosentan

Tablets 62.5 mg, 125 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Manufacturer #17691

Manufacturer usually replies in 7 days

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Bosentan

Bosentan is used to treat high blood pressure in a condition called pulmonary arterial hypertension, which effects the lungs. PAH is a condition that is caused by increased levels of an endothelin-1 in the body. It reduces the number of open wounds, especially on fingertips and knuckles. Bosentan is a dual endothelin receptor antagonist, in that it selectively inhibits the production of the substance Endothelin-1. The goal of Bosentan therapy is to improve ability to exercise and slow the progression of the disease. Bosentan has been shown effectiveness mostly in patients with symptoms that were rated as WHO Functional Class II-III.
In the USA, the European Union and other countries, the license of owned by Actelion Pharmaceuticals and sold under the trade name Tracleer.
Bosentan was approved for treatment for PAH in the US in 2001and in Europe in 2002.

Forms and Dosage

Bosentan is sold in film-coated tablets in strengths of 62.5 mg or 125 mg. It is also sold as dispersible tablets for oral suspension of 32 mg. Bosentan is administered as a single dose of 2000 mg/day for 2 months.
Bosentan harms fetuses so pregnant women are not prescribed this medicine, moreover, women taking Bosentan should not get pregnant. In the US, only doctors who follow an FDA-mandated risk evaluation and mitigation strategy (REMS) with respect to risks to fetuses and its risks of causing liver damage are allowed to prescribe it.

The wholesale cost of Bosentan

The average wholesale price is $49.50 per day for both 62.5 mg and 125 mg tablets and $2,970 per month in the USA. The same dose will cost 1510 pounds in the UK.
The price of Bosentan is significantly lower in the developing world, with the leading Indian brands costing only USD1 for 20 tablets of the same strength as sold in the USA or UK.
How does Bosentan work?
Bosentan is an antagonist of endothelin-1. When functioning normally, endothelin-1 causes the pulmonary blood vessels to constrict. Endothelin also causes abnormal growth of the muscle of the blood vessels in the lungs thus narrowing passages. This increases the pressure required to push the blood through the lungs to get oxygen. Conversely, Endothelin-1 has been associated with both vasodilation and vasoconstriction of vascular smooth muscle and tissue. Bosentan blocks the receptors, causing a total decrease in pulmonary vascular resistance.
Bosentan blocks off the effects of endothelin-1, which helps lower blood pressure in the lungs, slow the worsening of symptoms from the disease. Because it can reduce the stress on the lungs it also improves our ability to exercise and related research studies have verified this improvement.

Finding Bosentan Manufacturers and Suppliers

The process of finding trusted Bosentan manufacturers and Bosentan suppliers can be made quicker and more accessible by using Pipelinepharma's online platform, a B2B marketplace that lets you finalize the deals of pharmaceutical products in a matter of a few clicks. Also, it is an easy to use online platform to grow your business opportunities.
The robust search engine makes it convenient to search for manufacturers and suppliers of Bosentan. The search can be further refined with industry-specific filters such as dossier type, country of origin, GMP approvals, and search criteria for Wholesaler, etc. helping to get in contact with the preferred manufacturer and supplier readily.