What is BENZYLPENICILLIN PROCAINE?
Procaine benzylpenicillin (INN) is a pharmaceutical drug that is also known as procaine G penicillin, is an injectable antibiotic. It is an unsuccessfully soluble salt form of penicillin which is a union of naturally occurring benzylpenicillin (penicillin G) and the local anesthetic agent procaine in equimolar amounts. It is controlled by deep intramuscular injection. It is slowly incorporated and hydrolyzed to benzylpenicillin. This drug is used where increased illness to benzylpenicillin at a low intensity is wanted. This combination is pointed at subduing the pain and embarrassment associated with a profound intramuscular injection of penicillin. It is extensively employed in veterinary backgrounds. Benzylpenicillin is working decorating a wide spectrum of plants and is the formula of the first opportunity for many viruses.
For the achievement of a number of bacterial germs such as syphilis, anthrax, mouth infections, pneumonia, and diphtheria.
It is an antibiotic against penicillin-susceptible microorganisms with a bactericidal consequence. Alike all penicillins, procaine benzylpenicillin interferes with the synthesis of the bacterial cell wall peptidoglycan. It acts through the reserve of biosynthesis of cell-wall peptidoglycan, contributing to the cell wall osmotically unpredictable. It is part of the penicillin and beta-lactam order of antibacterial medications.
This pharmaceutical substance is hydrolyzed into penicillin G once it is released from the injection site. Penicillin G attaches to the penicillin-binding proteins on the bacterial cell wall and frustrates the transpeptidation enzyme that crosslinks the peptide chains appended to the backbone of the peptidoglycan. The final bactericidal event involves the inactivation of an inhibitor of autolytic enzymes in the cell wall, leading to lysis of the bacterium 4.
Procaine benzylpenicillin is compared with pain at the injection site, blood clotting problems, and seizures. Medication targeted against syphilis is often associated with Jarisch-Herxheimer’s reaction. The main undesired effects are hypersensitivity reactions caused by the debasement products of penicillin, which link with organism protein and become antigenic. Other common adverse effects include skin rashes, fever, and delayed serum sickness. Rare but fatal anaphylactic shock may occur. Oral LD50 values in mouse and rat are > 2000 mg/kg. Overdosage posterior causes convulsions, paralysis, and even death. Emesis and gastric lavage may be of value if begun within a few hours of injection. Excessive blood concentrations can be lowered by hemodialysis 6.
How does BENZYLPENICILLIN PROCAINE work?
This pharmaceutical substance is an antibiotic against penicillin-susceptible microorganisms with a bactericidal effect. Like all penicillins, procaine benzylpenicillin impedes the synthesis of the bacterial cell wall peptidoglycan.
The Wholesale Price of BENZYLPENICILLIN PROCAINE
The cost for penicillin g potassium injectable powder for injection (5,000,000 units is $79 for a hoard of 10 powder for this pharmaceutical medicine, depending on the pharmacy you hit.
Sourcing BENZYLPENICILLIN PROCAINE Manufacturers and Suppliers
PipelinePharma has found 4 verified benzylpenicillin procaine manufacturers and benzylpenicillin procaine suppliers of our global list of sellers. The pharmaceutical drug is available for sale in different forms such as powder for suspension for injection, solution for injection, powder for suspension for injection from manufacturers in various countries including European Union, China.
PipelinaPharma is a global B2B pharmaceutical online marketplace, which is structured so as to explain pharmaceutical proceedings by providing you with an intuitive interface that is easy to engage with. The selection of benzylpenicillin procaine expiations can be narrowed down with the use of filters and easily counterbalanced against one another according to medication prices and financial terms.