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Anagrelide manufacturers

10 products found

Filters

10 products found

anagrelide

Tablets 0.5mg, 1mg

Dossier type
EU CTD
Country of origin
European Union
Dossier status
Ready
GMP approvals
EU GMP

Manufacturer #17195

It is a pharmaceutical firm based in Central Europe that has spent the last ten years focusing on the development, production, and distribution of specialty medications. Good Manufacturing Practices and Good Distribution Practices are met by the medications. Bioequivalence and bioavailability tests have validated the medications' safety and efficacy.

Manufacturer usually replies in 7 days

anagrelide

Capsules 0.5 mg

Dossier type
EU CTD
Country of origin
European Union
Dossier status
Ready
GMP approvals
EU GMP
Unavailable markets
United Kingdom

Manufacturer #17263

It is a privately owned company that is devoted to long-term commitment, high quality, and continuity. For a small number of very special diseases, the company is the sole supplier of some key therapeutic agents throughout the world. Over the past 25 years, the group has become an established provider of integrated therapy solutions. the company has been able to position itself as an innovative front-runner in the development of effective therapies and drugs.

Manufacturer usually replies in 12 days

anagrelide

Tablets 0.5 mg/0.75 mg/1.0 mg

Dossier type
EU CTD
Country of origin
India
Dossier status
Ready
Clinical data
Bioequivalence
GMP approvals
EU GMP
Unavailable markets
Netherlands, United Kingdom
Registered in
Netherlands

Manufacturer #13666

Manufacturer usually replies in 2 days

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Anagrelide

Anagrelide is a drug used for the treatment of essential thrombocytosis or a condition in which the body overproduces blood platelets. Anagrelide use decreases the number of platelets cells needed to control bleeding, in patients suffering from bone marrow disorder. In this disease, body makes too much of one or other types of blood cells, such as essential thrombocythemia or polycythemia vera. While it is not chemotherapy, some of the hospitals classify it as chemotherapy as it can interfere with cell development, and the prescribing regulations similar to those governing a chemotherapy drug.
Anagrelide is especially recommended when the normal course of medication hasn’t worked, the patient has a history of Thrombosis, age above 60 and has a platelet count lower than 1000X109/L.
Anagrelide is commonly sold as Agrylin/Xagrid, Shire and Thromboreductin.
Takeda Pharma in USA first filed for a patent to manufacture Anagrelide (AGRYLIN) in 1997. Anagrelide, in its oral form, imidazoquinazoline was first approved for use in the US in 1997 and later approved for production in 1998. Anagrelide controlled release is currently in the third phase of clinical trials by Galena Biopharma for the treatment of essential thrombocytosis.

Dosage and forms

Anagrelide is sold in the form of a capsule. It is taken orally. The starting adult dose of Anagrelide is 0.5 mg which can be increased to 1 mg. the daily maximum dose limited at 2.5 mg. normally the patients will experience good responses at a median dose of 2-2.5 mg/day. As the medication is taken over time, the body should witness the platelet counts begin to decrease within 7-10 days of starting the course.

Cost of Anagrelide

In the USA, the consumer on an average have to pay USD 273 for a pack of 100 tablets with prescription-strength of 500mg, whereas the same supply costs significantly higher at 404 pounds in the UK. In the developing world, it costs USD 235, slightly cheaper than in the USA. However, the prices in the USA can vary depending on the insurance and discounts being offered to people on the different program in order to reduce the overall cost of the treatment.

How does Anagrelide work?

Anagrelide works by inhibiting the maturation of platelets from megakaryocytes. The exact mechanism of action is unclear, although it is known to be a phosphodiesterase inhibitor. Anagrelide is in a class of drugs named platelet-reducing agents. These agents work by slowing the production of platelets in the body. But it is hypothesized that Anagrelide selectively suppresses bone marrow megakaryocytes by interfering with the maturation process thus decreasing platelet production.

Finding Anagrelide Manufacturers and Suppliers

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