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Anagrelide manufacturers

9 products found

Filters

9 products found

anagrelide

Tablets 0.5mg, 1mg

Dossier type
EU CTD
Dossier status
Ready to file
Country of origin
European Union
GMP approvals
EU GMP
Manufacturer #17195
It is a pharmaceutical firm based in Central Europe that has spent the last ten years focusing on the development, production, and distribution of specialty medications. Good Manufacturing Practices and Good Distribution Practices are met by the medications. Bioequivalence and bioavailability tests have validated the medications' safety and efficacy.

Manufacturer usually replies in 7 days

anagrelide

Capsules 0.5 mg, 1 mg

Dossier type
EU CTD
Dossier status
Ready to file
Country of origin
European Union
GMP approvals
EU GMP
Manufacturer #313

A pharmaceutical manufacturer based in the EU that has been active in 50+ countries selling its products in Europe, North America, LATAM, and Asia for 10+ years. Key production lines are Rx, OTC, and nutraceuticals. Main therapeutic areas include the respiratory system, dermatology, and cardiovascular system. The company possesses several branches in LATAM

Manufacturer usually replies in 7 days

anagrelide

Tablets 0.5 mg, 0.75mg, 1.0mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
EU GMP
Manufacturer #17488

Manufacturer usually replies in 2 days

anagrelide

Capsules 0.5 mg

Dossier type
EU CTD
Dossier status
Ready to file
Country of origin
Turkey
GMP approvals
Turkey
Available for
Licensing with supply, Distribution only
Comments
Reference Product : Thromboreductin
Manufacturer #2748
It is a privately held pharmaceutical company based in southeast Europe that was established in the 1990s to import and introduce pharmaceutical items into medicine. The company began by importing hemophilia and intensive care supplies, as well as immunoglobulin-containing items. To suit market demands, the company has added additional dermatological, cardiological, urological, and surgical goods to its portfolio since then. They now offer a diverse product line that includes not only prescription but also OTC, medical gadgets, and dermo-cosmetics.

Manufacturer usually replies in 7 days

anagrelide

Capsules 0.5 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
Indonesia
GMP approvals
Indonesia
Manufacturer #20700

Manufacturer usually replies in 5 days

anagrelide

Tablets 500 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Manufacturer #18530

Manufacturer usually replies in 4 days

anagrelide

Capsules 0.5mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
South Korea
GMP approvals
PICS
Manufacturer #17197
It is an integrated healthcare company founded in the 1920s. It has achieved top market value and sales revenue in the local pharmaceutical industry and has been awarded as the most respected and trusted company in East Asia for more than 10 years. The core business of the company can be classified into primary & specialty care, dietary supplements, household & animal care, and contract manufacturing of active pharmaceutical ingredients.

Manufacturer usually replies in 9 days

anagrelide

Capsules 1mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
South Korea
GMP approvals
PICS
Manufacturer #17197
It is an integrated healthcare company founded in the 1920s. It has achieved top market value and sales revenue in the local pharmaceutical industry and has been awarded as the most respected and trusted company in East Asia for more than 10 years. The core business of the company can be classified into primary & specialty care, dietary supplements, household & animal care, and contract manufacturing of active pharmaceutical ingredients.

Manufacturer usually replies in 9 days

anagrelide

Capsules 0.5 mg, 1 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
Argentina
GMP approvals
PICS
Manufacturer #16454
A pharmaceutical company based in South America with 15+ years of experience in a drug market. More than 40 products in 25+ countries: LATAM; Wester, Southern and South-eastern Asia. Company’s therapeutic areas consist of products that can used in such areas as: urology, oncology, rare diseases and more.

Manufacturer usually replies in 7 days

Anagrelide

Anagrelide is a drug used for the treatment of essential thrombocytosis or a condition in which the body overproduces blood platelets. Anagrelide use decreases the number of platelets cells needed to control bleeding, in patients suffering from bone marrow disorder. In this disease, body makes too much of one or other types of blood cells, such as essential thrombocythemia or polycythemia vera. While it is not chemotherapy, some of the hospitals classify it as chemotherapy as it can interfere with cell development, and the prescribing regulations similar to those governing a chemotherapy drug.
Anagrelide is especially recommended when the normal course of medication hasn’t worked, the patient has a history of Thrombosis, age above 60 and has a platelet count lower than 1000X109/L.
Anagrelide is commonly sold as Agrylin/Xagrid, Shire and Thromboreductin.
Takeda Pharma in USA first filed for a patent to manufacture Anagrelide (AGRYLIN) in 1997. Anagrelide, in its oral form, imidazoquinazoline was first approved for use in the US in 1997 and later approved for production in 1998. Anagrelide controlled release is currently in the third phase of clinical trials by Galena Biopharma for the treatment of essential thrombocytosis.

Dosage and forms

Anagrelide is sold in the form of a capsule. It is taken orally. The starting adult dose of Anagrelide is 0.5 mg which can be increased to 1 mg. the daily maximum dose limited at 2.5 mg. normally the patients will experience good responses at a median dose of 2-2.5 mg/day. As the medication is taken over time, the body should witness the platelet counts begin to decrease within 7-10 days of starting the course.

Cost of Anagrelide

In the USA, the consumer on an average have to pay USD 273 for a pack of 100 tablets with prescription-strength of 500mg, whereas the same supply costs significantly higher at 404 pounds in the UK. In the developing world, it costs USD 235, slightly cheaper than in the USA. However, the prices in the USA can vary depending on the insurance and discounts being offered to people on the different program in order to reduce the overall cost of the treatment.

How does Anagrelide work?

Anagrelide works by inhibiting the maturation of platelets from megakaryocytes. The exact mechanism of action is unclear, although it is known to be a phosphodiesterase inhibitor. Anagrelide is in a class of drugs named platelet-reducing agents. These agents work by slowing the production of platelets in the body. But it is hypothesized that Anagrelide selectively suppresses bone marrow megakaryocytes by interfering with the maturation process thus decreasing platelet production.

Finding Anagrelide Manufacturers and Suppliers

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