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Xylometazoline hydrochloride manufacturers

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Country of origin : Switzerland

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xylometazoline hydrochloride

Nasal drops 0.05%, 0.1%

Dossier type
EU CTD
Dossier status
Ready to file
Country of origin
Switzerland
GMP approvals
EU GMP
Manufacturer #17471

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Xylometazoline Hydrochloride manufacturers

Xylometazoline Hydrochloride is used to relieve nasal congestion caused by a cold, seasonal allergies, or other lung allergies for a short period of time. Xylometazoline is an atropine drug that causes nasal mucosal vascular constriction. The median time of beginning of subjective reduction of nasal congestion was about 1.7 minutes in one research of participants with nasal congestion associated with the common cold, and the time of subjective peak relief of nasal congestion lasted 30 minutes. Long-term use of xylometazoline has been linked to rebound edoema, nasal congestion, rhinitis medicamentosa, and a shorter duration of decongestant effect in healthy volunteers, implying that the medicine is most effective when used momentarily.

How does Xylometazoline Hydrochloride work?

Xylometazoline reduces nasal stiffness and increases nasal airflow volume during inspiration and expiration. It demonstrated a slightly faster onset of action than oxymetazoline, another imidazoline nasal decongestant, but having a similar duration of treatment. Various etiologies, such as rhinosinusitis and allergic or non-allergic rhinitis, produce nasal congestion, resulting in congestion of the venous sinusoids underlying the nasal mucosa. The activation of -adrenergic receptors causes the blood vessels of the nasal mucosa to constrict, allowing nasal airflow to resume. 1A- and 2B-adrenoceptors, which are the most abundantly expressed in the human nasal mucosa, may have the most essential function in nasal mucosa vascular constriction.

The Wholesale Price of Xylometazoline Hydrochloride

It is available at every drugstore. Based on the drugstore you visit, the Xylometazoline liquid drop costs roughly $10 for a supply of 100 ml. The price varies from pharmacy to pharmacy. Pharmaceutical corporations generally support patient assistance programmes (PAPs), which provide free or subsidised drugs to low-income, uninsured, or the under-insured patients who meet certain criteria.

Sourcing the Xylometazoline Hydrochloride Manufacturer and Suppliers

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Quality Assurance

To keep up to the quality standards other than Good Manufacturing Practice approvals that this medicine manufacturers list has, we qualify their companies before they are boarded on the platform. This allows us to screen Xylometazoline Hydrochloride manufacturers for the quality of the pharmaceutical products’ dossiers and protect against the risk of possible malpractices.