Trypsin: chymotrypsin
Trypsin Chymotrypsin is used in the treatment of pain relief and swelling. Trypsin:
chymotrypsin is an oral proteolytic enzyme, in since the 1960s. It has better ability to resolve
inflammation and promotes faster recovery of acute tissue injury than of the other existing
enzymes. It relieves surgical pain or pain related to any kind of injury. An injury increases
levels of some chemicals that signal pain to the brain. Its actions reduced the level of
chemicals reducing pain. Many millions around the world suffering from impaired tissue
repair leading to Chronic wounds. Chronic wounds are significantly higher in morbidity,
mortality, and leading to poorer quality of life. In addition, it causes a significant financial
burden to treat such chronic conditions. Effective and prompt management of acute tissue
injury is the only to avoid letting them become a chronic wound.
Trypsin: chymotrypsin is sold under the brand names Chymocad, Chymocip and chymoral
forte amongst others.
Richardson Merrell Inc filed the first patent application in 1959. It comes into commercial use
The 1960s. However, after the expiry of the initial patent, several other companies now have their
own formulations.
Dosage and administration
Trypsin:chymotrypsin is sold as tablets in the 48mg and 90mg and other strengths. The
dose for each case depends on the severity of the injury or the recovery needed. For an
exact dose, consulting the doctor with your condition is recommended.
Price of Trypsin Chymotrypsin
In India, the consumers have to pay USD5.5 for a supply of 20 tablets of Trypsin
Chymotrypsin.
How does Trypsin Chymotrypsin Work?
Trypsin Chymotrypsin is an enzyme. It actions break down proteins into smaller fragments.
This makes them easily available for absorption into the blood. After absorption, it increases
blood supply to the affected area to reduce swelling.
After administration, Trypsin + Chymotrypsin gets absorbed into the circulatory system and
exerts the action of alpha-1 anti-trypsin and alpha-2 macroglobulin. This leads to the
degradation of such factors. These mediators are responsible for fibrinolytic shutdown and
maintenance of inflammatory delaying the healing process. Trypsin + Chymotrypsin improve
plasmin action and clears the microcirculation. This reduces edema and facilitates the
healing process.
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https://patents.google.com/patent/US3004893A/en
https://patents.justia.com/patents-by-us-classification/435/213
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778189/
https://www.webmd.com/vitamins/ai/ingredientmono-405/chymotrypsin
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-
science/chymotrypsin-trypsin
https://www.1mg.com/generics/trypsin-chymotrypsin-210879