Tibolone which is also known under the popular brand names of Livial, Tinox, Tibofem, and others. Is a medication which is used in menopausal hormone therapy and in the treatment of postmenopausal osteoporosis and endometriosis. It is taken by mouth and is typically produced by manufacturers alone as a single non-combination drug. Tibolone was originally developed by manufacturers in the 1960s and was subsequently brought to the global medical marketplace in 1988, following regulatory approval. Currently, tibolone manufacturers and tibolone suppliers market it throughout the world, however, it is notably not available in the United States or Canada. Regardless, it is frequently found on the pharmaceutical products for sale list of distributors, where it can be found wholesale across the global marketplace at a variety of cost and price points.
Mechanism of action of tibolone:
Tibolone belongs to a group of drugs which function as synthetic steroid hormones. It is mainly non-selective in its binding profile, acting as an agonist primarily at estrogenic receptors, with a preference for estrogen receptor-alpha. Its effects are primarily owed to the activity of its metabolites in various tissues. As post-consumption, tibolone is rapidly converted into various metabolites which have varying progestogenic and androgenic effects. These metabolites are subsequently dispersed through circulation where they come into contact with their target receptors located in varying tissue types. This binding to the target receptors initiates a series of downstream effects that culminate in the observed clinical properties of the medication.
Form and dosage of tibolone:
The final form and packaging of tibolone is dependent on the manufacturers and suppliers, as well as the particular distributors and order. However, tibolone predominantly is found for sale in tablet form, where it is taken by mouth for the treatment of oestrogen deficiency and osteoporosis prophylaxis in women at high risk of bone fractures. A typical prescribed dose is 2.5 mg daily, however, this can be adjusted based on patient need by the prescribing healthcare professional.
Tibolone on Pipelinepharma:
Currently, at the time of writing, we have found 3 verified tibolone manufacturers and tibolone suppliers from our online global list of B2B sellers. These manufacturers, suppliers, and distributors are located in countries including Brazil and Argentina. Each company and their pharmaceutical products list listed on our online wholesale B2B platform has been verified by the Pipelinepharma team. This ensures seller reputability while reducing sourcing mileage and hassle.
Price of tibolone and how to buy:
A cursory search online reveals an approximate cost for 28 x 2.5 mg tablets of tibolone to be £10.36 for wholesale to the NHS in the United Kingdom. However, as with all drugs, the specific price will be highly dependent on the individual buyer. Therefore the prices indicated above solely serve as generalizations of the current market pricing and not a definitive guide. Although prices on the online Pipelinepharma marketplace are confidential, manufacturers may choose to list the desired cost for their product to facilitate a quick transaction. If so, this will be indicated alongside an ‘Accept’ and ‘Negotiate’ button, with a ‘Get offer’ button being displayed in the absence of a listed price.