Tenofovir disoproxil is a medication that is used to prevent or treat HIV/AIDS as well as to treat chronic hepatitis B. Tenofovir disoproxil manufacturers produce both drug formulations with it as the standalone ingredient, as well as combination drugs, wherein it is coupled with other active ingredients, such as emtricitabine, lamivudine, efavirenz, and many others. Suppliers of tenofovir disoproxil market it in the form of 123mg, 163mg, 204mg, and 245mg oral tablets. First approved for medical use in 2001, the drug was introduced into the market by the manufacturer and supplier Gilead Sciences under the trade name tenofovir disoproxil. It has since then become included in the World Health Organization’s list of Essential Medicine that contains the most important medications recommended for a basic health system. The two largest manufacturers of tenofovir disoproxil are currently major pharmaceutical companies Gilead Sciences and GlaxoSmithKline. Tenofovir disoproxil suppliers and distributors market both generic and trade name formulations of the drug.

Tenofovir is a member of a group of antiretroviral medications called nucleotide analogue reverse transcriptase inhibitors (NtRTIs), which prevent reverse transcriptase, an enzyme required for virus generation in HIV-infected people. By reducing viral replication, this makes it possible to regulate the HIV viral load. The fumarate salt of the drug carrier tenofovir disoproxil is called tenofovir disoproxil fumarate. Tenofovir disoproxil is absorbed and changed into tenofovir, a nucleoside monophosphate analogue, which is the active form. Then, constitutively produced enzymes in the cell transform tenofovir into its active metabolite, tenofovir diphosphate, a chain terminator. By directly competing with the natural ribonucleic acid substrate (deoxyadenosine 5'-triphosphate), tenofovir diphosphate inhibits the HIV-1 reverse transcriptase and the Hepatitis B polymerase and, after integrating into DNA, induces viral DNA chain breakage.

The retail prices of tenofovir disoproxil-inclusive medications vary, depending on the other active ingredients included in the formulation, on whether it is a generic or trade name medication, and on supplier and manufacturer pricing. Costs per 30 (200mg/245mg) emtricitabine/tenofovir disoproxil medications can range from 80 EUR to 700 EUR. However, the price of Tenofovir Disoproxil is higher than that of such substitutes, owing largely to the more costly manufacturing process needed to produce it. Also, the costs of Tenofovir Disoproxil vary depending on manufacturer and supplier pricing, whether it is a generic or trade name formulation, concentration of the active ingredient in the formulation. It is available or sale at every medical store. Tenofovir Disoproxil suppliers, on the whole, are in favor of patient aid initiatives. Tenofovir Disoproxil is available for sale from various Tenofovir Disoproxil vendors at multiple costs.

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Being a global B2B pharmaceutical online marketplace, Pipelinepharma is structured to simplify pharmaceutical deals by providing you with an intuitive interface that is easy to engage with. The selection of Tenofovir Disoproxil offerings can be narrowed down with filters and easily weighed against one another according to medication prices and commercial terms. The advanced filters help you filter out the countries for this substance manufacturer and Tenofovir Disoproxil suppliers that you are looking for. These also enable you to check the dossier status of this medicine and the GMP approvals of the different variants of Tenofovir Disoproxil. Also, each manufacturer or supplier product description contains essential information about this substance, including clinical data, stability zones, and countries in which Tenofovir Disoproxil is already registered. Manufacturers also have special delivery terms.

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