Ranitidine, commonly sold as Zantac, is available both as a prescription and OTC drug. It is a derivative of histamine receptor antagonists. This pharmaceutical drug is used in the treatment of bowel diseases, Gastroesophageal Reflux Disease (GERD), stomach ulcer diseases, and Zollinger–Ellison syndrome. It is also used to treat heartburn. It was approved by FDA for but later was called for withdrawal due to a substance called N-Nitroso dimethylamine (NDMA), which can cause the risk of malignancy if this pharmaceutical substance is consumed for prolonged period.
It may be used as a combination therapy with other medicines to increase the duration and quality of action. Ranitidine is usually manufactured as a tablet but may be available in other forms as well such as effervescent tablets or granules and oral syrup. It is prescribed as a single dose taken once or twice a day. It is better to take it an hour before your meal.
This pharmaceutical substance is not suitable for pregnant and lactating women, as its breakdown by-product NDMA may cause harm to the mother as well as to the organs of the developing fetus, and it may be secreted in the breastmilk. People aged 40 and above, or who have a previous history of bowel malignancy, or use anti-inflammatory medicines, should not take this drug.
The side effects caused by Ranitidine are mild. These go away without any medication, which include headache, upset stomach, watery bowels, nausea, vomiting, or abdominal pain.
How Does Ranitidine Work?
The following pharmaceutical remedy acts by nulling or decreasing the secretion of acids in the gut. It antagonizes the action of histamine, which is present in the epidermal layer of the stomach and stimulates the release of gastric acid. Thereby, causing a sense of relief in a person who experiences burning sensation.
The Wholesale Price of Ranitidine:
The wholesale price of a pair of oral tablets 150mg is $5 whereas for a pack of syrup it may cost $0.71.
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