Pravastatin is from a group of medicines called statins. They are used to lower LDL, bad
cholesterol levels, and triglycerides and increases HDL, the good cholesterol in patients
diagnosed with high blood cholesterol. It is also used to prevent heart disease, including
strokes and attacks, especially with those at high risk and treating abnormal lipids.
Pravastatin is used in conjunction with diet, weight, and physical activity of the patient. When
used properly with diet as prescribed, the real benefit of using Pravastatin is that it
decreases the odds of heart ailments occurring, removing the need for surgical intervention
in people with existing heart conditions and even those who are at the risk of developing
Pravastatin is sold as Pravachol among others.
Pravastatin got its first approval in 1991 when it became only the second statin sold in the
United States. It was the first statin administered as the active form. Sankyo Co. Ltd.
developed Pravastatin drug, however, the first approved product was approved by FDA in
1991 and was developed by Bristol Myers Squibb.
Pravastatin was first patented in 1980. Later, Sankyo first developed Pravastatin and was
launched for medical use in 1989. In 2017, with more than 24 million prescriptions, it was
one of the most commonly prescribed medications in the United States.
Pravastatin is sold as tablets which are sold in the increasing strengths of 10, 20, 40 and
80mg doses. For the prevention of coronary events and cardiovascular events, the dosage
starts with 10mg per day going up to 40 mg per day.
In more than 112,000 patient-years of tests using the 40-mg, once-daily dose and placebos,
Pravastatin has proved that it is well tolerated by our body and has very few non-heart
related abnormalities in patients.
How does Pravastatin work?
Pravastatin belongs to a class of medications which are statin inhibitors. The medicine works
by slowing the cholesterol production in the body thus decreasing the excess cholesterol that
may get built upon the walls of the arteries leading to blocked blood flow to the brain, heart
and other vital organs of the body
Pravastatin works by preventing the liver from stop making cholesterol. This lowers your
blood cholesterol level. For the first 12 months on this medicine, patients are tested a couple
of times routinely to make their liver is working normally. A patient treated with Pravastatin
have their cholesterol levels drop significantly within 4 weeks
The wholesale cost of Pravastatin
The most common version of pravastatin 10mg tablets sells at the lowest price of 0.21 USD
in the USA and costs 0.95 Pounds in the UK. In India, it costs 1.32 to 2.20 USD per 10 mg
tablet depending on the brand, consumer that decides to buy.
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Elisor (Baowei Technology Group) / Lipostat (Bristol-Myers Squibb) / Mevalotin (Daiichi
Sankyo) / Pravaselect / Selipran (Bristol-Myers Squibb)
Actavis Pharma Company , Bioenhance Medicines Inc, Mantra Pharma Inc