Povidone is an iodine antiseptic that causes in vivo denaturation of protein, bacterial precipitation, and ultimately the death of harmful microorganisms. As a result, it's good for disinfection and sterilisation. It has a minimal toxicity to humans and can destroy viruses, germs, spores, fungus, and protozoa.
Polyvinylpyrrolidone with elemental iodine forms a stable chemical combination called povidone-iodine. On a dry weight basis, it contains between 9.0 percent and 12.0 percent accessible iodine. H. A. Shelanski and M. V. Shelanski discovered this unique complex in the Industrial Toxicology Laboratories in Philadelphia in 1955. The complex was found to be less toxic in mice than tincture of iodine during in vitro testing to demonstrate antibacterial activity. The product outperformed other iodine solutions in human clinical testing. Povidone-iodine was quickly commercialised and has now become the most widely used iodine antiseptic.
How does Povidone work?
Povidone-iodine is an iodophor, that means it works as an iodine transporter. Microbicidal effects are mediated by iodine, which is the active moiety. Free iodine (I2) penetrates the cell wall of microorganisms fast after being released from the complex, and the deadly effects are thought to be caused by disruption of protein and nucleic acid structure and production. Iodine is considered to block critical bacterial cellular systems and structures, as well as oxidise nucleotides, fatty acids, and amino acids in bacterial cell membranes, while the exact method of action is unknown.
Pricing of Povidone
Depending on the drugstore you visit, this medicinal iodine topical topical solution 10% costs roughly $11 for a supply of 60 millilitres. The patient pools who may be able to finance the treatment are being questioned, despite the fact that local charges are thought to be significantly cheaper than those in the United States.
Supplying Povidone Manufacturers and Suppliers
Navigating our pharmaceutical marketplace
Being a global B2B pharmaceutical online marketplace, Pipelinepharma is structured to simplify pharmaceutical deals by providing you with an intuitive interface that is easy to engage with. The selection of Povidone offerings can be narrowed down with the use of filters and easily weighed against one another according to medication prices and commercial terms. The advanced filters help you filter out the countries for these substance manufacturers and these substance suppliers that you are looking for. These also enable you to check the dossier status of this medicine, and the GMP approvals of the different variants of Povidone. Also, each manufacturer or supplier product description contains essential information about this substance including clinical data, stability zones, countries where Povidone is already registered in. Manufacturers also have special, and delivery terms.
Establishing commercial ties
If you are a pharmaceutical licensing company or a distributor you can enter into deals or negotiations over this medicine offer with manufacturing companies after completing the free registration process and joining our online marketplace. This helps to ensure that you conclude the pharmaceutical deal at a reasonable cost and achieve the best cost/benefit ratio for your company while bypassing lengthy sourcing, negotiation, and ordering process. Once you have finalized a deal, you can look forward to a long-lasting business relationship with the manufacturers or suppliers. This way, the marketplace allows you as a distributor to skip the process of shortlisting product manufacturers every time you are looking for in-licensing or distribution deals.
To keep up to the quality standards other than Good Manufacturing Practice approvals that this medicine manufacturers list has, we qualify their companies before they are boarded on the platform. This allows us to screen Povidone manufacturers for the quality of the pharmaceutical products’ dossiers and protect against the risk of possible malpractices.