Medroxyprogesterone Acetate Manufacturers
Medroxyprogesterone acetate belongs to a class of Progestogen drugs, this medication is indicated to treat secondary amenorrhea, to reduces the incidence of endometrial hyperplasia in postmenopausal women, and to treat abnormal uterine bleeding due to hormonal imbalance.
Medroxyprogesterone acetate is advised as a prescription product, generic prescription product as well as mixture product.
Before using this medication, the risk of taking the drug must be weighed against the benefits it provides. It is always recommended to consult a physician before taking Medroxyprogesterone acetate as this medication may interact with other drugs and health problems.
Medroxyprogesterone acetate is marketed by manufacturers under the brand name of Provera, Meprogest, Proclaim. This drug is available only with the doctor’s prescription and is available in the dosage form of Tablet and Injection, Suspension.
Tablet form is available in a dosage strength of 2.5 mg, 5 mg, and 10 mg which is taken orally, and Injection is available in a dosage strength of 104 mg/0.65 mL, 150 mg/mL, 400 mg/mL which is administered intramuscularly. The shot must be injected into the thigh, buttock, or deltoid muscle four times a year (every 11 to 13 weeks) and provides pregnancy protection instantaneously after the first injection.
Medroxyprogesterone acetate is also available in a lower dosage. Medroxyprogesterone acetate can be injected using a smaller injection needle inserting the medication just below the skin, instead of into the muscle, in either the abdomen or thigh. This subcutaneous injection claims to reduce the side effects of Medroxyprogesterone acetate while still maintaining all the same benefits of the original intramuscular Medroxyprogesterone acetate.
The usual adult dose for endometrial hyperplasia prophylaxis is 5 mg or 10 mg oral tablet taken daily for 12 to 14 days per month.
The recommended dose of Medroxyprogesterone acetate injection for contraception is 150 mg once every 3 months (13 weeks) administered intramuscularly in the deltoid or gluteal muscle. And the 104 mg subcutaneous injection is administered every 3 months (12-14 weeks) into the anterior thigh or abdomen.
Medroxyprogesterone acetate vials must be stored upright at controlled room temperature 20° C to 25° C (68° F - 77° F).
Wholesale price of Medroxyprogesterone Acetate
The wholesale price for 150 mg/1mL medroxyprogesterone intramuscular suspension cost $ 7.50 - % 68.45 for 1 millilitre.
The cost for medroxyprogesterone intramuscular 150 mg/mL suspension is around $ 954.60 - $1483.32 for a supply of 25 milliliters and per-unit cost ranges between $ 38.18 - $ 59.33.
The wholesale price of 2.5 mg medroxyprogesterone oral tablet for a set of 30 tablets costs $13.25 with per unit cost comes at $ 3.12 and for a set of 30 tablets, it costs approximately $ 100, with per unit cost of $ 0.44.
Medroxyprogesterone acetate - Mechanism of action
Medroxyprogesterone acetate inhibits the production of gonadotropin by preventing follicular maturation and ovulation, which is responsible for its ability in preventing pregnancy. Medroxyprogesterone acetate reduces nuclear estrogen receptors and DNA synthesis in epithelial cells of the endometrium.
Finding Medroxyprogesterone Acetate Manufacturers and Suppliers
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