Magaldrate belongs to the drug class of Antacids, Magaldrate is used for the treatment of severe heartburn, sour stomach, acid indigestion, hyperphosphatemia, and magnesium deficiency.
Magaldrate is also used off-label to treat gastric and duodenal ulcers and gastroesophageal reflux disease (GERD).
Magaldrate is also an inorganic salt that neutralizes the excess acid in the stomach. Magaldrate is an antifoaming medicine that disintegrates gas bubbles and allows easy passage of
gas. The drug also acts as a local anesthetic which provides faster relief from pain due to ulcers or acidic injury in the stomach. Magaldrate is also used to relieve symptoms of extra gas such as belching, bloating, and feelings of pressure and discomfort in the stomach or gut.
Magaldrate also helps in breaking up gas bubbles in the gut. Liquid antacids formulation of magaldrate usually works faster than tablets or capsules. Acids reflux, which also includes regurgitation, bitter taste, persistent dry cough, pain when lying down, and trouble swallowing. Heartburn, which has a burning sensation in the chest or throat caused by acid reflux indigestion, is the pain in the upper gut that can feel like gas or bloating.
Magaldrate is advised as the mixture product as well as an over-the-counter product. Manufacturers market
Magaldrate under the Brand name of Almadrat, Lowsium, Mason, Losopan, Riopan to name a few. This medication is available in the dosage form of suspension, tablets, and capsules and is administered orally. Suspension form is available in the dosage strength of 540mg/5mL, 40mg/5mL. Tablet form is available in dosage strength of 480 mg.
Antacids class of drugs can also interfere with the absorption of many other drugs. This product may also
contain inactive ingredients, which can cause allergic reactions or other problems. Please talk to your doctor or inform your doctor before prescribing the product about our allergies. The total dose of capsule or tablet must not to exceed 2000 mg per day or as prescribed by the physician. For Heartburn, Sour stomach, and acid Indigestion the recommended dosage is 5-10 mL (1-2 teaspoonfuls; 540-1080 mg) between meals and at bedtime; not to exceed 80 mL (16 teaspoonfuls) in 24-hour period.
Tablets and Capsules should be stored at room temperature between 15° C to 30° C (59° F - 86° F) away from heat and light.
Wholesale Price of Magaldrate
In the US market, the wholesale price of Magaldrate oral tablets costs around $ 44.90 for a set of 24 tablets.
Magaldrate - Mechanism of action
Magaldrate neutralizes the production of gastric acid, by reducing the direct acid irritant effect. The drug increases gastric pH, which inactivates pepsin production. Magaldrate also enhances the production of mucosal barrier integrity and improves the gastroesophageal sphincter tone.
Magaldrate reduces the acid reaching the duodenum by neutralizing the acid present in the stomach. The salt mechanism of neutralization of acid varies, and each salt has a different mechanism with the goal of acid neutralization. It may be used alone or with other medications that lower acid production which includes H2 blockers and proton pump inhibitors such as omeprazole and other enzymes.
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