Lornoxicam belongs to a class of new nonsteroidal anti-inflammatory drugs (NSAID) of the oxicam class which is an analgesic with anti-inflammatory and antipyretic properties.
Lornoxicam is mainly used for pain relief. Lornoxicam relieves pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis.
Lornoxicam works by blocking the release of the certain chemical messengers which are responsible for the inflammation, pain and swelling.
Before using Lornoxicam, the risk of taking the drug must be weighed against the benefits it provides. It is always recommended to consult a physician before taking Lornoxicam as this medication may interact with other drugs or health problems.
Manufacturers market Lornoxicam drugs under the Brand name of Acabel, Bosporon, Lorflex, Lorcam.
Lornoxicam comes in the dosage form of film-coated tablet which is taken orally and is available in 4 mg and 8 mg dosage strengths. The daily recommended dose of Lornoxicam is 8 -16 mg which is divided into 2 or 3 doses and the maximum daily dose should not exceed 16 mg.
Lornoxicam is also available in powder and solvent for solution for injection which is available in dosage strengths of 8 mg administered intramuscularly or intravenously. Daily dose of Lornoxicam injections is 8 mg and the maximum daily dose should not exceed 16 mg.
Patients with liver or kidney impairment, should not take more than 12 mg (taken twice or three times a day) of this medicine. For patients with arthritis the recommended dose is 12 mg, divided in two or three doses per day which should not exceed more than 16 mg a day.
This Drug Lornoxicam is contraindicated in the patients who must not be taking other NSAIDs, possible reasons which are said to be seen are salicylate sensitivity, gastrointestinal bleeding, and bleeding disorders, with severe impairment of heart, liver and kidney function. Lornoxicam is not at all recommended during pregnancy of the patient and breastfeeding is contraindicated during the last trimester of pregnancy.
The approved storage conditions for Lornoxicam are to store at a temperature not above 30° C (86° F).
Wholesale Price of Lornoxicam
In the US market, the wholesale price of Lornoxicam oral tablet 4 mg costs around $ 0.56 for a set of 10 tablets and for a set 100 Lornoxicam oral tablet 4 mg costs around $ 5.6.
The cost of Lornoxicam oral tablet 8 mg costs $ 0.91 for a quantity of 10 tablets and for a set 100 Lornoxicam oral tablet 8 mg it costs around $ 9.1.
The cost for Lornoxicam 8 mg vial is around $ 36.40 for 5 vials and the cost for lornoxicam 8mg/2ml for 5 vials is $ 46.80.
Lornoxicam - Mechanism of action
Lornoxicam ability of anti-inflammatory and analgesic activity is related mainly to the structure of inhibitory action on prostaglandin and thromboxane synthesis along with the inhibition of both COX-1 and COX-2, which mainly leads to the reduction of inflammation, pain, fever, and swelling, the symptoms which are mainly mediated by prostaglandins.
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