Lymecycline belongs to the class of tetracyclines and the type of antibiotic which is mainly indicated to treat acne.
Lymecycline is a broad-spectrum second-generation tetracycline antibiotic which is also used for other susceptible bacterial infection such as bronchitis, pneumonia, and mycoplasma infections, some sexually spreading infections, and trachoma, few more infections can be treated by this class of tetracyclines include upper respiratory tract infections, urinary tract infections, chlamydial infections, and rickettsia infections.
Lymecycline is marketed by manufacturers under the Brand name of CycloPel 300 mg, Damelium, Eficiclina. It is issued on prescription only.
Before using this medication, the risk of taking the drug must be weighed against the benefits it provides. It is always recommended to consult a physician before taking Limecycline as this medication may interact with other drugs and health problems.
Lymecycline is available in the dosage form of capsule and injection. The capsule is administered orally while the injection is administered via the intramuscular route. This drug is available in a dosage strength of 100 mg, 150 mg, 300 mg, 408 mg.
Lymecycline capsules are red and yellow and are available in a carton pack containing 28 or 56 capsules packed in polyethylene/foil blisters. Each blister strip contains 4 capsules and there are 7 or 14 blister strips in each carton pack. Each capsule contains 408mg of lymecycline.
The dosage and length of treatment are based on your medical condition and response to treatment.
The normal dose of Limecycline for acne in adults and children over 12 years is a one lymecycline capsule once a day, preferably in the morning.
Limecycline capsules are not recommended for use in children under 12 years of age as it can cause permanent discoloration of tooth enamel and also affect bone development of bone.
Acne responds slowly to antibiotics and it is important that one should take all the lymecycline capsules that are prescribed.
Limecycline capsules should be stored in an original container not above 25° C (77° F).
Wholesale Price of Limecycline
The cost for equivalent drugs of lymecycline oral capsule 100 mg is around $ 28 for a supply of 14 capsules and the per-unit cost is available for $ 1.68 and the lowest available per unit cost is $ 1.36 for a set of 500 tablets.
Limecycline - Mechanism of action
Lymecycline antibiotics are protein synthesis inhibitors. They inhibit the start-up of translation in a variety of ways by binding the 30S ribosomal subunit, which is mainly made up of 16S rRNA and other 21 proteins. All the enzymes inhibit the binding of aminoacyl-tRNA to the mRNA translation complex. Lymecycline is lipophilic and can diffuse across the bacterial cell membranes by traveling through membrane porin channels. Aminoacyl tRNA binding inhibition most likely occurs through steric hindrances by managing the binding units. Lymecycline results in the inhibition of bacterial protein synthesis and hence cell growth are initiated effectively.
Lymecycline, like other tetracyclines, exerts bacteriostatic actions on the intracellular and extracellular bacteria and their group which cause infections and by treating susceptible bacterial infections.
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