Ivermectin is a generic pharmaceutical medicine that tackles parasite infections, such as ascariasis, scabies, and strongyloidiasis. This pharmaceutical drug is used medicinally on human patients. It is also very widespread as a veterinary medication.
Ivermectin businesses produce standalone ivermectin formulations and also use them as a segment in mixture drugs along with other components, such as albendazole.
Ivermectin is an antiparasitic medication that is used to treat various parasitic infections in humans and animals. It was first discovered in the 1970s and was initially used to treat parasites in animals such as cattle, sheep, and horses. Later, it was approved for humans treatment of the parasitic infections such as river blindness, strongyloidiasis, and scabies. Ivermectin has been included in the World Health Organization's (WHO) List of Essential Medicines.
Ivermectin is an FDA-approved drug that was first introduced in the 1980s. The drug's patent is held by Merck & Co., Inc. The original patent for Ivermectin expired in 1996 in the United States, which allowed other pharmaceutical companies to produce and market generic versions of the drug. However, Merck still holds patents on various formulations and applications of Ivermectin.
Ivermectin is now available in brand names: Sklice, Soolantra, Stromectol, Posela and others.
Ivermectin is available in various forms and strengths for both human and animal use, including tablets, creams, and lotions, and is often given as a single dose.
In humans, it is available as an oral tablet with strengths ranging from 3mg to 12mg, depending on the indication for use. It is also available in topical formulations, such as creams and lotions, with strengths of 1% or 2%.
However, it should only be used under the guidance of a healthcare provider, as incorrect use or overuse can lead to side effects such as nausea, vomiting, and diarrhea.
Is Ivermectin approved for the treatment of COVID-19?
It's important to note that Ivermectin has not been approved for the prevention or treatment of COVID-19, and there is currently not enough evidence to support its use for this purpose. The World Health Organization (WHO) and the US Food and Drug Administration (FDA) have not recommended Ivermectin for COVID-19 treatment outside of clinical trials.
Ivermectin works by targeting the nervous system of certain parasites and causing paralysis and death. It binds to specific glutamate-gated chloride ion channels present in the nerve and muscle cells of the parasite, causing an increase in the permeability of the cell membrane to chloride ions. This leads to hyperpolarization of the nerve or muscle cell, resulting in paralysis and, eventually, death of the parasite.
This mechanism of action is specific to certain parasites and is not present in humans, which is why Ivermectin is generally safe for use in humans at recommended doses. In addition to its antiparasitic activity, some evidence suggests that Ivermectin may have anti-inflammatory and antiviral effects. However, more research is required to confirm these potential benefits.
It's important to note that while Ivermectin has been successfully used to treat a range of parasitic infections in humans and animals, there is currently not enough evidence to support its use for the prevention or treatment of COVID-19.
The wholesale price of Ivermectin can vary depending on the formulation, strength, and country where it is being sold. In general, the cost of Ivermectin is relatively low, especially compared to many other prescription medications. However, it's worth noting that the price can vary depending on the manufacturer, supplier, and market demand.
In many countries, Ivermectin is available as a generic medication, which helps to lower the cost.
For example, in the United States, the price of a single 3mg Ivermectin tablet can range from around $0.20 to $3.00, depending on the pharmacy and insurance coverage. The expense for Ivermectin lingual dose 3 mg is around $79 for a supply of 20 tablets, depending on the drugstore.
In Europe, Ivermectin's pack size of four 3mg tablets in wholesale costs around 26.20 EUR in Poland, 9.50-14.10 EUR in France and 17.50 EUR in Spain.
The wholesale price of 30g of 10mg/g Ivermectin cream is 13.6 EUR in Poland, whereas retail price of the same product fall into the range of 20.00 EUR to 30.00 EUR.
The market for the drug is relatively fragmented, with multiple producers and suppliers vying for market share. There are several pharmaceutical companies that manufacture and supply Ivermectin globally, including Merck, Galderma, Zoetis, and Cipla Limited, among others. These companies are typically regulated by the FDA, EMA or other national regulatory agencies to ensure quality and safety standards are met.
Ivermectin suppliers and distributors market both generic and trade name formulations of the drug. Online sellers may attempt to market fraudulent versions of the generic drug, whereas Pipelinepharma, through its quality control procedures, ensures that only verified Ivermectin manufacturers and suppliers enter our online marketplace, offering you risk-free B2B pharmaceutical partnerships.
Finding trusted Ivermectin manufacturers and suppliers can be made quicker and more accessible using Pipelinepharma's online platform. It is easy to use the platform to grow your business opportunities. Convenient search engine makes it easy to search for manufacturers and suppliers of Ivermectin.
The selection of Ivermectin options can be narrowed down with filters and easily evaluated against one another according to drug prices and commercial terms. The advanced filters help you search for available Ivermectin manufacturers by product ATC class, form, dossier type and readiness, country of origin, GMP approvals and more.
Also, each product card contains essential information about this substance, including clinical data, CPP, stability zones, shelf life, packs, batch sizes, MOQ, available deal types, countries where Ivermectin is already registered or where the specific manufacturer cannot supply the product.
All this information is available to Pipelinepharma registered users and can be seen by logging into the platform free of charge.