Human insulin, commonly referred to simply as insulin, is the predominant hormone responsible for regulating blood sugar levels in the human body. As such, it has a long history of medicinal use for the treatment of diabetes, which is characterized by elevated levels of blood glucose, caused by its non-regulation by insulin. It was originally produced by the drugs manufacturing company Nordisk Insulin laboratorium in 1923 and following refinement in subsequent years, in 1946 Nordisk formed crystals of protamine and insulin and put it on the medical marketplace in 1950. This new form was called neutral protamine Hagedorn (NPH) insulin, also known as biphasic isophane insulin, which although taking longer to act, continues to act for longer conferring additional benefits.
Although newer formulations are available, human insulin manufacturers and human insulin suppliers still list it for sale to distributors on the global marketplace, where it can be found for wholesale at varying price points. This is in a large part driven by it and its derivatives being on the World Health Organization's List of Essential Medicines, indicating it as a cost-effective and efficient medication recommended for use in health systems around the globe.
Method of action of human insulin:
Human insulin belongs to a group of pharmaceutical products in the insulin hormone family which all predominantly function through similar pathways. As an outline, post-injection, it initially binds to the insulin receptors on cells located in the body. This triggers the liver, muscle, and fat cells to increase their uptake of glucose from the bloodstream, while also decreasing the production of glucose by the liver and triggering various downstream effects. As glucose is removed from the bloodstream, this reduces blood sugar levels. Therefore, excess blood sugar in ailments such as diabetes can be controlled through the modulated addition of insulin.
Form and dosage of human insulin:
As with all drugs, the final form and packaging are dependent on the specific manufacturers and suppliers, as well as the intended distributors and order. However, it can typically be found for both wholesale and sale in forms including suspension for injection, solution of injection, prefilled syringe, vials, and concentration for infusion for injection. This is a prescription medication, as such, it should only be taken if recommended by a medical professional. Typical dosages will vary upon the individual patient and their need, however, typically it is taken once or twice a day subcutaneously at 100 units/mL. With its effects having an onset of 1–4 hours and its peak being 6–10 hours, with a duration of approximately 10–16 hours.
Human insulin on Pipelinepharma:
Currently, we have found a list of 10 trusted human insulin manufacturers and human insulin suppliers from our global online list of B2B wholesale sellers, located in countries including Ukraine, the European Union, Argentina, Egypt, and Indonesia. These manufacturers and suppliers have been verified by the Pipelinepharma team according to strict quality control. This serves to reduce both sourcing mileage and transaction time to allow for a painless experience for all parties.
Price of human insulin and how to buy:
A cursory search online reveals that human insulin 100units/mL suspension for injection (3mL) is typically sold at a wholesale cost of USD 20.40 to the NHS. This is however, highly dependent on many factors such as location, organisation, and manufacturers. Although the cost of purchase is confidential between both B2B parties on the Pipelinepharma online marketplace, purchase and price inquiries can easily be submitted through the inbuilt interface.