Hyaluronic acid sodium
Hyaluronic acid sodium is used to treat knee pain in patients with osteoarthritis or joint
inflammation. It is prescribed in cases where treatment with acetaminophen, exercise, or
physical therapy has failed to produce desirable results. Hyaluronic acid could also be used
in plastic surgeries to reduce wrinkles or as a filler in other parts of the body.
It is also used
in ophthalmology surgeries, like in the extraction of cataracts, implantation of intraocular
lenses, corneal transplants, glaucoma filtration, and retinal attachment, and the treatment of
dry eyes. Hyaluronic acid is also used to treat interstitial cystitis, where it works by coating
the lining of the bladder.
Hyaluronic acid sodium is sold under the brand name Recosyn, Synvisc, Viscure, and Yardel
amongst others. It is sold under several other brand names in other countries.
FDA-approved Hyaluronic acid to treat osteoarthritis of the knee. In high molecular weights,
HA improved both pain and function in people with knee osteoarthritis. Karl Meyer and John
Palmer first obtained it in 1934 from cow's eye. Pharmacia developed the first hyaluronan
biomedical product, in the 1970s and 1980s, and approved for use in eye surgery such as
corneal transplantation, cataract surgery, glaucoma surgery, and surgery to repair retinal
detachments.
Forms and Dosage:
The hyaluronic acid sodium salt is available as a solution for injection, cream, or gel or soft
gel capsules in the strength of 0.2% concentration. The patient is recommended to apply a
thin layer without rubbing too intensely onto the wound surface. This process can be
repeated two or three times per day. The patient is also advised to cover the lesion area with
a sterile gauze pad or a compressive or elastic bandage. Each tube of this medicine is for
single-patient use only to reduce the risk of cross-infection.
In Adults, for aging skin when taken orally, the medicine is used daily for 3 months. In the
treatment of osteoarthritis, the administration is done for 3 months. When applied to the skin,
for dry eye, Eye drops containing 0.1% to 0.3% hyaluronic acid is used 3 to 8 times a day,
for swelling and sores inside the mouth it can be mixed with water and used as a mouth
rinse. And by injection, when used for aging skin, the patient has injected a hyaluronic acid
into skin wrinkles and while treating osteoarthritis the same hyaluronic acid is injected into
the joint.
The price of Hyaluronic acid sodium
In the global wholesale market, the consumers have to pay USD 300 for the supply of 50
grams of the ingredient version of this medicine. In India, the consumers have to pay USD
250 for a 20ml injection and the cost of this medicine is higher still in the developed world.
How does it work?
Hyaluronic acid work just like a substance that occurs naturally in our joints. Its action serves
as a lubricant and shock absorber in the joint. It helps the knee in moving smoothly, thereby
lessening pain. It does this by modulating interactions between adjacent tissues. It is a vital
polysaccharide distributed extensively in the extracellular matrix of connective tissue. As it is
highly viscous, it can protect ocular tissues and cell layers. The elasticity of the solutions
aids in the absorption of mechanical stress and creates a protective buffer for the tissues.
When used in wound healing, it protects the vehicle that transports peptide growth factors
and other structural proteins to the site of action. Once it has transported key molecules, it
degrades and transports proteins to promote tissue repair.
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https://en.wikipedia.org/wiki/Hyaluronic_acid
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