Gefitinib manufacturers sell this Drug under various Brand names like Gefinter, Gefinor, and Iressa. Gefitinib is available in the form of film-coated tablets with the dosage strength of 250mg, which is administered orally once daily and is absorbed slowly with a mean bioavailability of 60%. The dose is the same for both male and female patients irrespective of age and weight.
The approved storage conditions for Gefitinib are to be stored at room temperature 20 C – 25 C (68 F- 77 F) under the original package to protect from moisture.
Wholesale Price of Gefitinib
In the US region, the price of Gefitinib ranges from $6.5 - $8.6 per pill or unit, and the cost can go up to $229 to $604 for the quantity of 60 to 90 tablets, which are available in Aluminum / PVC perforated, or non-perforated blisters.
Gefitinib - Mechanism of Action
Gefitinib belongs to the Therapeutic class (a group of medicines) of Antineoplastic agents, which is pharmacologically a Tyrosine kinase inhibitor. Tyrosine Kinase is a type of protein that delivers signals telling cancer cells to grow. Gefitinib works by blocking the action of tyrosine kinase by inhibiting these signals thereby preventing the cancer cells from growing and multiplying.
Thus, Gefitinib inhibits EGFR tyrosine kinase by binding to the adenosine triphosphate (ATP) binding site of the enzyme with a protein binding capacity of almost 90%.
Finding Gefitinib Manufacturers and Suppliers
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