Entacapone is a medication used to treat Parkinson’s disease. An antagonist of catechol-O-methyltransferase is entacapone. It is used in conjunction with levodopa and carbidopa to address the Parkinson's disease symptoms that appear after a dose has worn off. Levodopa and carbidopa function more effectively thanks to entacapone because it allows more of them to enter the brain, where they have their effects. Manufacturers of entacapone produce formulations with it as the standalone ingredient as well as use it in combination drugs, along with carbidopa and levodopa. And entacapone suppliers market it in the form of oral tablets. The developer and earliest manufacturer of entacapone is Orion Pharma, who first introduced it into the market in 1998. Since then, other producers and suppliers have joined the market for the drug, including well-known pharmaceutical companies Teva, Mylan, Sun Pharma, Stada Arzneimittel, and others. Entacapone suppliers and distributors market both generic and trade name formulations of the drug.
How Does Entacapone Work?
Entacapone's method of action is thought to involve its capacity to block COMT in peripheral tissues, which changes the pharmacokinetics of levodopa in the plasma. Levodopa plasma rates are elevated and more sustained when entacapone is administered along with valproate and an aromatic amino acid decarboxylase blocker like carbidopa than when levodopa and an aspartic decarboxylase inhibitor are administered separately. It is thought that these longer-lasting plasma levels of levodopa cause more continuous dopaminergic activation in the brain at a specific frequency of valproate administration, which results in a greater reduction in the parkinsonian syndrome symptoms.
Wholesale Price of Entacapone
Retail prices per 100 (200mg) tablets of entacapone fall into an approximate range of 30 EUR to 70 EUR, while the costs for the equivalent amount of levodopa/carbidopa/entacapone medications can cost anywhere from 40 EUR to 70 EUR. Entacapone is available for sale from various Entacapone vendors at various costs. The prices of Entacapone medications vary depending on the concentration of active ingredients in the formulation as well as supplier and manufacturer pricing. Also, the costs of Entacapone vary depending on manufacturer and supplier pricing, whether it is a generic or trade name formulation, concentration of the active ingredient in the formulation. Entacapone suppliers, on the whole, are in favor of patient aid initiatives. The price of Entacapone is higher than that of such substitutes, owing largely to the more costly manufacturing process needed to produce it.
From Where to Get Entacapone?
Making use of Pipelinepharma's worldwide B2B online marketplace for medications and other pharmaceuticals is the ideal approach to locate and acquire access to Entacapone manufacturers and suppliers. Buyers are advised that online sellers may attempt to market fraudulent versions of the generic drug, whereas Pipeline Pharma, through its pre-auditing and quality control procedures ensures that only verified Entacapone manufacturers and wholesalers enter our online marketplace, offering you a risk-free B2B pharmaceutical sales platform. Finding reliable suppliers and manufacturers of particular medications like Entacapone can typically be a time-consuming challenge, but with Pipelinepharma's straightforward search engine and network of tested partners, the entire process becomes much simpler. Utilizing our built-in search engine, all you have to do to begin going is start looking for potential Entacapone suppliers or manufacturers. You may also use filters to narrow down your search results and look for Entacapone from particular nations.
Navigating our Pharmaceutical Marketplace
Being a global B2B pharmaceutical online marketplace, Pipelinepharma is structured to simplify pharmaceutical deals by providing you with an intuitive interface that is easy to engage with. The selection of Entacapone offerings can be narrowed down with filters and easily weighed against one another according to medication prices and commercial terms. The advanced filters help you filter out the countries for this substance manufacturer and Entacapone suppliers that you are looking for. These also enable you to check the dossier status of this medicine and the GMP approvals of the different variants of Entacapone. Also, each manufacturer or supplier product description contains essential information about this substance, including clinical data, stability zones, and countries in which Entacapone is already registered. Manufacturers also have special delivery terms.
Establishing Commercial Ties
Suppose you are a pharmaceutical licensing company or a distributor. In that case, you can enter into deals or negotiations over these medicine offers with manufacturing companies after completing the free registration process and joining our online marketplace. This helps ensure that you conclude the pharmaceutical deal at a reasonable cost and achieve the best cost/benefit ratio for your company while bypassing lengthy sourcing, negotiation, and order process. Once you have finalized a deal, you can look forward to a long-lasting business relationship with the Entacapone suppliers. This way, the marketplace allows you as a distributor to skip the process of making a list of product manufacturers every time you are looking for in-licensing or distribution deals.
To keep up to the quality standards other than Good Manufacturing Practice approvals that this medicine manufacturers list has, we qualify their companies before they are boarded on the platform. This allows us to screen Entacapone manufacturers for the quality of the pharmaceutical products' dossiers and protect against the risk of possible malpractices.