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Doxofylline manufacturers

43 products found

Filters

43 products found

doxofylline

Tablets 400 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
FDA
Manufacturer #18850

Manufacturer usually replies in 2 days

doxofylline

Tablets 400 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
Bangladesh
GMP approvals
FDA, EU GMP
Manufacturer #21340

Manufacturer usually replies in 9 days

doxofylline

Tablets 400 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Manufacturer #21177

Manufacturer usually replies in 12 days

doxofylline + montelukast

Tablets 400 mg + 10 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Manufacturer #21177

Manufacturer usually replies in 12 days

doxofylline

Tablets 400 mg, 800 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Manufacturer #20350

Manufacturer usually replies in 4 days

doxofylline

Tablets for oral solution 400 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Manufacturer #19861

Manufacturer usually replies in 3 days

doxofylline

Tablets 400 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Manufacturer #19698

Manufacturer usually replies in 3 days

doxofylline + montelukast sodium

Tablets 400 mg+10 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Manufacturer #19328

Manufacturer usually replies in 1 days

doxofylline

Tablets 400 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Manufacturer #18273

Manufacturer usually replies in 1 days

doxofylline

Tablets 400 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Manufacturer #17798

Manufacturer usually replies in 4 days

doxofylline + glucose

Solution for injection 300 mg - 100 ml

Dossier type
CTD
Dossier status
Ready to file
Country of origin
China
GMP approvals
China
Manufacturer #12677

Manufacturer usually replies in 4 days

doxofylline + glucose

Injection 100ml:0.3g:5g

Dossier type
CTD
Dossier status
Ready to file
Country of origin
China
GMP approvals
WHO
Manufacturer #17087

Manufacturer usually replies in 3 days

doxofylline

Solution for injection 0.2g

Dossier type
CTD
Dossier status
Ready to file
Country of origin
China
GMP approvals
China
Manufacturer #13622

Manufacturer usually replies in 6 days

doxofylline

Injection 10 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Manufacturer #20259

Manufacturer usually replies in 9 days

doxofylline

Tablets for oral solution 400 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Manufacturer #19735

Manufacturer usually replies in 8 days

doxofylline

Tablets 400mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Manufacturer #19412

Manufacturer usually replies in 5 days

doxofylline

Tablets 400 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Manufacturer #20394

Manufacturer usually replies in 15 days

doxofylline + montelukast

Tablets 400 mg+10 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Manufacturer #19255

Manufacturer usually replies in 11 days

doxofylline

Tablets 400mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Manufacturer #18510

Manufacturer usually replies in 11 days

doxofylline

Tablets 400 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO
Manufacturer #20499

Manufacturer usually replies in 75 days

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Doxofylline

Doxofylline is a new kind of Bronchodilator that is a Methyl xanthine derivative. It treats COPD, asthma, and bronchospasm, inhibit platelet-activating factor and generation of leukotriene production. Structurally, Doxofylline differs from Theophylline as the dioxolane group in Doxofylline is in position 7. Doxofylline select and then inhibits phosphodiesterase 4. The resulting benefit the relaxing of bronchial smooth muscle. Even though different, it still has low affinities toward adenosine A1 and A2 receptors, giving the drug, a better safety profile. Doxofylline is reported to be marketed under many brand names like Xiva, An Li Nuo Er, An Sai Ma worldwide by several manufacturers. Alistair Pharmaceuticals demonstrated efficacy similar to theophylline but with significantly fewer side effects in 2013. By 2014, it received an orphan drug designation to doxofylline for the treatment of bronchiectasis by the US FDA.

Dosage & Administration

Doxofylline is available as 200 and 400mg tablets and sustained-release tablets. The standard adult dose for the Elderly is 200 mg tablets, taken 2 to 3 times a day. For adults, the dose is set at 400 mg tablet, taken 2 to 3 times, or as directed by the physician. In treating children, the dose for kids younger than 12 years of age is 10 ml syrup or 200 mg tablets, taken 2 to 3 times a day. For kids between 6-12 years of age, the dose is 6-9 mg for every kg of body weight, taken 2 to 3 times a day. For a body weight of 10 kg, a dose of 3 ml or 60 mg is prescribed. When the daily dose needed is 400 mg, the user can take the SR tablet, once a day.

The cost of Doxofylline

In the USA, the consumer pay USD43 for a supply of 60 tablets of 400mg. In India, the retail cost of 60 tablets of 400 mg, the same quantity as in the USA will cost around USD8.

How does Doxofylline Work?

Although its main mechanism of action is unclear, it is thought to inhibit phosphodiesterase activity in turn lifting cAMP levels and promoting smooth muscle relaxation. Doxofylline Interaction with beta-2 adrenoceptors, Serine 169, and serine 173 residues in the receptor critical binding sites. This is where the hydrogen bonds are formed by mediating actions of beta-2 adrenoceptors, Doxofylline stimulates blood vessel relaxation and airway smooth muscle relaxation. It may also have anti-inflammatory actions in decreasing pleurisy induced by the inflammatory mediator platelet-activating factor in animal studies.

Finding Doxofylline Manufacturers and Suppliers:

The process of finding trusted Doxofylline manufacturers and Doxofylline

suppliers can be made quicker and more accessible by using Pipelinepharma's online platform, a B2B marketplace that lets you finalize the deals of pharmaceutical products in a matter of a few clicks. Also, it is easy to use an online platform to grow your business opportunities. The robust search engine makes it convenient to search for manufacturers and suppliers of Doxofylline. The search can be further refined with industry-specific filters such as dossier type, country of origin, GMP approvals, and search criteria for Wholesaler, etc. helping to get in contact with the preferred manufacturer and supplier readily.