Doxifluridine could be a second-generation nucleoside analog prodrug created by Roche and utilized as a cytostatic specialist in chemotherapy in a few Asian countries including China and South Korea. Doxifluridine isn't FDA-approved for utilizing within the USA. It is as of now being assessed in several clinical trials as a stand-alone or combination treatment. High thymidine phosphorylase expression is additionally found within the human intestinal tract, coming about in dose-limiting harmfulness (the runs) in a few people. The foremost visit unfavorable impacts of Doxifluridine were neurotoxicity and mucositis.
How does Doxifluridine work?
A fluoropyrimidine subordinate and verbal prodrug of the antineoplastic operator5-fluorouracil (5-FU) with antitumor action. Doxifluridine planned to delude the speedy degradation of 5-FU by dihydropyrimidine dehydrogenase in the gut wall, is turned into 5-FU in the nearness of pyrimidine nucleoside phosphorylase.
The Wholesale price of Doxifluridine
It is obtainable in generic and brand versions. It is not covered by most Medicare and insurance plans, but pharmacy coupons can help balance the cost. In the US, The cost of Doxifluridine 1g is $78. Prices may vary on the pharmacy you visit.
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