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donepezil

Tablets, orally disintegrating (ODT) 5mg, 10mg

Dossier type
EU CTD
Dossier status
Ready to file
Country of origin
European Union
GMP approvals
EU GMP
Manufacturer #425
A pharmaceutical manufacturer based in Europe that has been active in Europe for 20+ years. Main therapeutic areas include CNS, urology, and cardiovascular system. The key production line is Rx. The main dosage form is solid form.

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Donepezil is a centrally acting reversible acetylcholinesterase inhibitor, belonging to a class of medications called Acetylcholinesterase inhibitors. It improves mental function such as memory, attention, the ability to interact with others, speak, think clearly, and perform regular daily activities by increasing the amount of certain naturally occurring substances in the brain. Donepezil is used to treat dementia – a brain disorder that affects ability to remember, think clearly, communicate and perform daily activities and may cause changes in mood and personality in people having Alzheimer’s disease where it is used to increase cortical acetylcholine. Donepezil manufacturers sell this Drug under the Brand name drug Aricept. It is also available as a generic drug. Donepezil comes in two tablet forms namely film coated tablet and disintegrating tablet which can be taken once a day via oral route. It is also available in solution form. This medication can be taken by Adults only and not recommended for pediatric use as a treatment for any medical condition. The tablet dosage form of Donepezil is available in 5 mg, 10 mg, 23 mg dosage strengths. The 5 mg tablets are white, 10 mg tablets are yellow and 23 mg tablets are reddish in color. The oral disintegrating tablets are available in 5 mg, 10 mg dosage strengths. The 5 mg tablets are white, 10 mg tablets are yellow. Both the tablet forms are engraved with brand name on one side and dosage strength on the other side. The Oral solution form is available in 1 mg/1mL dosage strength. The recommended storage conditions of Donepezil tablets / orally disintegrating tablets are to store in the original container it came, at a controlled room temperature between 15° C to 30° C (59° F - 86° F). Wholesale Price of Donepezil The wholesale price of 30 units of 5 mg Donepezil oral tablet is approximately $ 7.50 with per unit cost comes at $ 0.25. The lowest available wholesale price for the quantity of 100 Donepezil tablets is $ 7.50 - $ 154.68 with per unit costs as low as $ 0.07 - $ 1.55 The per unit cost of 10 mg Donepezil oral tablet is approximately $ 0.25 - $ 2.25, which is available for a price range of $ 7.50 - $ 67.56 for 30 tablets whereas the per unit cost of 23 mg tablet is $ 1.85, which is available for $ 55.40 for a quantity of 100 tablets. The 5 mg and 10 mg Oral disintegrating tablets are available at a price range of $ 40.89 - $ 48.26 for a set of 30 tablets with per unit ranges between $ 1.46 - $ 1.72 Donepezil - Mechanism of Action Donepezil inhibits acetylcholinesterase, an enzyme responsible for the destruction of one neurotransmitter, acetylcholine. This leads to increased concentrations of acetylcholine in the brain, and the increased concentrations are believed to be responsible for the improvement seen during treatment with donepezil. Finding Donepezil Manufacturers and Suppliers Many times we tend to find manufacturers and suppliers by attending conferences, exhibitions etc. that is time consuming and is directly related to money, and we are not sure whether we get the trusted suppliers, which is a major constraint then. One can avoid this constraint by Pipelinepharma, which helps buyers in finding the trusted manufacturers and suppliers of Donepezil. Pipelinepharma, which is a business-to-business (B2B) licensing marketplace for pharmaceutical products which quickly connects owners with the consumer for the business development. One can filter the product names in a unified search engine by its country, category, therapeutic area, forms, dossier and its status, regulatory filings, approvals, and more.

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