Dofetilide is a drug that helps people who have atrial fibrillation keep their hearts beating normally (the upper chambers of the heart that allow blood to flow into the heart). Patients with atrial fibrillation or flutter are prescribed this medication. It is available in capsules containing 125, 250, and 500 mg of dofetilide in the United States under the brand name Tikosyn. It is not available in Europe or Australia.
It is a category III antiarrhythmic drug licenced by the Food and Drug Administration (FDA) for maintaining sinus tachycardia in those who are susceptible to atrial fibrillation as well as flutter, and also chemical cardiac cath from atrial fibrillation and flutter to sinus rhythm.
How does Dofetilide work?
It works by blocking the cardiac signaling pathway that carries the fast component of the postponed rectifier potassium wave, IKr. The action potential duration and the effective refractory period of accessory pathways are both lengthened as a result of potassium channel blockage, both anterograde and retrograde conduction in the accessory pathway.
This medicine is available in the form of a capsule to be taken by mouth. It is normally taken twice a day, although in some cases, it may just be used once a day. Follow the label instructions carefully, and if there is anything you don't understand, ask your doctor or pharmacist to explain it to you. It should be taken exactly as prescribed. It regulates but does not treat aberrant cardiac rhythms. Even if you feel fine, keep taking It.
Pricing of Dofetilide
Dofetilide is sold by a variety of manufacturers and distributors at various prices. Depending on the drugstore you visit, a supply of 40 dofetilide oral capsule 125 mcg costs roughly $163. Prices are only valid for cash paying consumers and do not apply to insurance programmes.
Supplying Dofetilide Manufacturers and Suppliers
Navigating our pharmaceutical marketplace
Being a global B2B pharmaceutical online marketplace, Pipelinepharma is structured to simplify pharmaceutical deals by providing you with an intuitive interface that is easy to engage with. The selection of Dofetilide offerings can be narrowed down with the use of filters and easily weighed against one another according to medication prices and commercial terms. The advanced filters help you filter out the countries for these substance manufacturers and this substance suppliers that you are looking for. These also enable you to check the dossier status of this medicine, and the GMP approvals of the different variants of Dofetilide. Also, each manufacturer or supplier product description contains essential information about this substance including clinical data, stability zones, countries where Dofetilide is already registered in. Manufacturers also have special, and delivery terms.
Establishing commercial ties
If you are a pharmaceutical licensing company or a distributor you can enter into deals or negotiations over this medicine offer with manufacturing companies after completing the free registration process and joining our online marketplace. This helps to ensure that you conclude the pharmaceutical deal at a reasonable cost and achieve the best cost/benefit ratio for your company while bypassing lengthy sourcing, negotiation, and ordering process. Once you have finalized a deal, you can look forward to a long-lasting business relationship with the manufacturers or suppliers. This way, the marketplace allows you as a distributor to skip the process of shortlisting product manufacturers every time you are looking for in-licensing or distribution deals.
To keep up to the quality standards other than Good Manufacturing Practice approvals that this medicine manufacturers list has, we qualify their companies before they are boarded on the platform. This allows us to screen Dofetilide manufacturers for the quality of the pharmaceutical products’ dossiers and protect against the risk of possible malpractices.