Docusate Sodium Manufacturers
Docusate Sodium is the sodium salt of docusate. Docusate, a dioctyl salt is a stool softener indicated for the treatment of constipation associated with dry and hard stools.
Docusate decreases surface tension and emulsification of fecal matter and allows water to penetrate and mix with stool where it softens the stool and makes it easier to pass. This is often used after a certain type of surgery like heart surgery when there is a strain to have a bowel movement.
Docusate Sodium belongs to a class of drugs called Laxatives, Stool Softener.
Docusate Sodium manufacturers market this drug under different Brand names like Colace, Dialose, Dominate, Surfak, Silence, and Rectalad Enema (pediatric only) to name a few. This medication is also available as over-the-counter products (OTC).
Docusate sodium is administered orally and rectally. This drug is available in the dosage form of a capsule, syrup, capsule (liquid-filled), solution, and tablet, all of which are taken by mouth. Docusate Sodium is available in various dosage strengths namely 50mg, 100mg, 200mg, 240mg, 10 mg/ml, 100mg/5mL (pediatric only).
The dosage consideration of Docusate Sodium for adults is 50 - 300 mg orally once daily or can be divided into doses. For children between 2 - 12 years of age, 50-150 mg orally once a day or divided doses is given, a dose of 50 - 300 mg orally is recommended daily for children over 12 years of age. For pediatric rectal, the recommended dose is 100mg/5mL (1 enema) rectally once a day or 283 mg/5mL (1 enema) rectally once a day is given for children between 2 - 12 years of age. It generally produces bowel movement in 12 - 72 hours.
This medication should be stopped if one has rectal bleeding or fail to have a bowel movement after it’s used. These could be a sign of serious conditions and one needs to consult a physician without any delay.
Docusate Sodium is recommended to store at a controlled room temperature of 15 C - 30 C (59 F - 86 F) in a tightly-closed container away from light and moisture.
Wholesale Price of Docusate Sodium
In the US, the wholesale price of Docusate Sodium 100 mg capsule is $ 8.18 for a set of 30 capsules and $ 5.50 for a bottle of 100 tablets. The cost for a set of 14 capsules of Docusate Sodium 100 mg capsule is $ 4.02
The lowest available price for 100 mg Docusate Sodium capsules for a quantity of 10 capsules is $ 2.70 which depends on the pharmacy one visits.
Docusate Sodium - Mechanism of Action
Docusate Sodium is a surface-active agent, it lowers the surface tension at the oil-water interface of the feces, allowing water and lipids to penetrate the stool, which results in hydration and softening of the fecal material facilitating natural defecation.
Finding Docusate Sodium Manufacturers and Suppliers
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