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Dimethyl fumarate manufacturers

19 products found

Filters

19 products found

dimethyl fumarate

Capsules, gastro resistant (GR) 120 mg, 240 mg

Dossier type
EU CTD
Dossier status
Ready to file
Country of origin
European Union
GMP approvals
EU GMP
Available for
Licensing with supply
Manufacturer #16163
As a result of a strategic agreement with a company delivering an attractive high-quality portfolio with European supply, it is a trustworthy B2B partner with more than 30 years of experience in the out-licensing business model. The organization is a reliable commercial partner that takes a customer-centric approach and strives for long-term partnership development to secure market success.

Manufacturer usually replies in 6 days

dimethyl fumarate

Capsules, hard liquid 120 mg, 240 mg

Dossier type
EU CTD
Dossier status
Ready to file
Country of origin
European Union
GMP approvals
EU GMP
Manufacturer #21467

Manufacturer usually replies in 4 days

dimethyl fumarate

Capsules 120 mg, 240 mg

Dossier type
EU CTD
Dossier status
Under development
Country of origin
European Union
GMP approvals
EU GMP
Comments
Ref: Tecfidera®
Manufacturer #252

Manufacturer usually replies in 2 days

dimethyl fumarate

Tablets 30 mg, 120 mg

Dossier type
EU CTD
Dossier status
Under development
Country of origin
European Union
GMP approvals
EU GMP
Manufacturer #21467

Manufacturer usually replies in 4 days

dimethyl fumarate

Oral suspension 120 mg/2 ml

Dossier type
EU CTD
Dossier status
Under development
Country of origin
European Union
GMP approvals
EU GMP
Comments
Modified release oral suspension. Early stage
Manufacturer #8593
It is a private R&D and business development organization established in the 2000s, specializing in the design and development of new pharmaceutical products worldwide. They have an average of 5-6 new developments per year, an average of 8-10 DCPs per year, more than 60 dossier updates in the last 10 years, they have more than 3 valid and approved patent applications, and approximately 140 MAs worldwide.

Manufacturer usually replies in 2 days

dimethyl fumarate

Capsules, gastro resistant (GR) 120 mg, 240 mg

Dossier type
EU CTD
Dossier status
Ready to file
Country of origin
European Union
GMP approvals
EU GMP
Unavailable markets
Portugal , Vietnam
Available for
Licensing with supply
Manufacturer #437
A pharmaceutical manufacturer based in the EU that is active in 40+ countries selling its products in Europe, North America, LATAM, Africa, Middle East, and Asia for 40+ years. Main therapeutics areas include the nervous system, cardiometabolic, and women’s health. The company's production lines are GMP-compliant. The main dosage forms are solid, semi-solid, liquid, and suspension. The company owns branches in the EU, Africa, and LATAM.

Manufacturer usually replies in 10 days

dimethyl fumarate

Capsules 120 mg, 240 mg

Dossier type
EU CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
EU GMP
Registered in
Italy
MAs for sale
Italy , Spain
Manufacturer #15189
The company, which was founded in 1989, is involved in developing, manufacturing, and distributing a wide range of formulations for anti-infectives, cardiovascular, anti-diabetic, dermatological, and hormone treatment. The corporation has a global presence in 170 + countries, 60+ WHO-prequalified medications, and 3700+ product registrations.

Manufacturer usually replies in 9 days

dimethyl fumarate

Capsules, gastro resistant (GR) 120 mg, 240 mg

Dossier type
EU CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
EU GMP
Unavailable markets
Chile , Vietnam , Panama
Available for
Licensing with supply
Manufacturer #261
A pharmaceutical manufacturer based in the EU that has been selling its products in Europe for 20+ years. Main therapeutic areas include diabetes, CNL, dermatology, and oncology. Main dosage forms include solid and liquid oral, sterile dosage forms, and ointments. The company possesses 10+ manufacturing facilities that are cGMP-compliant.

Manufacturer usually replies in 6 days

dimethyl fumarate

Capsules 120 mg, 240 mg

Dossier type
EU CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
EU GMP
Unavailable markets
Saudi Arabia
Manufacturer #1338

Manufacturer usually replies in 7 days

dimethyl fumarate

Capsules 120mg,240mg

Dossier type
EU CTD
Dossier status
Under development
Country of origin
Turkey
GMP approvals
EU GMP
Manufacturer #281
It is a leading European pharmaceutical firm that strives to create a powerful global brand with innovative goods and services, as well as bold and pioneering activities, by working passionately to heal the lives they touch. The business was founded in the 1900s. In the interest of public health and the national economy, the firm launched the project to promote public awareness about the unintentional use of medications.

Manufacturer usually replies in 8 days

dimethyl fumarate

Capsules, delayed release (DR) 120mg, 240mg

Dossier type
CTD
Dossier status
Under development
Country of origin
India
GMP approvals
EU GMP, WHO
Manufacturer #9258

Manufacturer usually replies in 4 days

dimethyl fumarate

Capsules 120 mg, 140 mg

Dossier type
EU CTD
Dossier status
Under development
Country of origin
India
GMP approvals
EU GMP
Manufacturer #21496

It's a fully integrated pharmaceutical corporation with a global reach. The company specializes in CMO and CDMO pharmaceutical preparations in a variety of dosage forms for a variety of therapeutic categories. GSK, Pfizer, Sanofi, Novartis, Mylan, Apotex, Adcock Ingram, and other MNCs manufacture formulations in various dosage forms for customers in 55 countries in important markets such as Europe, Australia & New Zealand, Canada, Japan, Far East Asia, GCC, Africa, LATAM, and CIS.

Manufacturer usually replies in 8 days

dimethyl fumarate

Capsules 120 mg , 240 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
Argentina
GMP approvals
PICS
Registered in
Argentina
Available for
Licensing with supply, Distribution only
Manufacturer #15733
One of the leading manufacturers in cosmetic and medicinal products in the South American Continent. The company has been committed since 1990-is to developing and manufacturing high-quality products that allow healing and improve someone’s life. They are a major exporter of its therapies to different regions such as Latin America and Asia. Medicine is manufactured for pain, gastroenterology, hepatology, and cardiology.

Manufacturer usually replies in 8 days

dimethyl fumarate

Capsules, delayed release (DR) 120mg, 240mg Ready to file Q3 2019

Dossier type
EU CTD
Dossier status
Under development
Country of origin
India
GMP approvals
EU GMP
Manufacturer #10897
A pharmaceutical manufacturer based in Asia that is active in 80+ countries selling its products in Europe, North America, Africa, the Middle East, CIS, LATAM, and Asia for 40+ years. The company's production lines are WHO GMP-compliant. The main dosage forms are tablets, capsules, dry syrups, suspensions, and injections. The main therapeutic areas include antifungal, analgesics, and psychotropics.

Manufacturer usually replies in 12 days

dimethyl fumarate

Tablets 120 mg , 240 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
Turkey
GMP approvals
PICS
Manufacturer #16875
In the 1920s, it was one of 150+ firms founded in southeast Europe. In its early years, it manufactured and marketed pharmaceutical items under the licensing of global corporations. In the early 1980s, the company began importing completed pharmaceutical items and manufacturing and marketing identical products, establishing itself as a major participant in the local pharmaceutical industry. For more than 50 years, it has provided the pharmaceutical business with more than 210 different pharmaceutical goods, over 70 brands, and the manufacture of high-quality drugs, and continues to work with international companies.

Manufacturer usually replies in 6 days

dimethyl fumarate

Capsules 120 mg, 240 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
Argentina
GMP approvals
Argentina
Manufacturer #16199
One of the largest and biggest names in the pharmaceutical industry. The company has a network all across the globe. They are known to be partnering with similar companies for a very long time.

Manufacturer usually replies in 9 days

dimethyl fumarate

Capsules 120mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
Turkey
GMP approvals
Turkey
Manufacturer #14913
With over 20 years of expertise, it is Europe's leading specialty pharmaceutical company. They collaborate with international pharmaceutical companies to deliver novel cures and solutions to our community. Working in accordance with ethical and scientific principles, the company aims to set the highest standards for quality, safety, and value in the manufacturing and distribution of healthcare goods.

Manufacturer usually replies in 9 days

dimethyl fumarate

Capsules, gastro resistant (GR) 120 mg, 240 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
Turkey
GMP approvals
PICS
Manufacturer #13095

Manufacturer usually replies in 5 days

dimethyl fumarate

Capsules 120 mg, 240 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
India
GMP approvals
WHO, EU GMP
Manufacturer #20273

Manufacturer usually replies in 21 days

Dimethyl fumarate

Dimethyl fumarate is the fumaric acid of the methyl ester. It is named after the earth smoke plant called Fumaria officinalis. Dimethyl fumarate treats various forms of multiple sclerosis, a disease in which the nerves do not function properly and people may experience weakness, numbness, loss of muscle coordination, and problems with vision, speech, and bladder control) among adults. These include clinically isolated syndrome, its nerve symptom episodes that last at least 24 hours, for relapsing-remitting forms or secondary progressive forms. Dimethyl fumarate is an Nrf2 activator, whose actions decrease inflammation and prevent nerve damage caused by multiple sclerosis. It has great immunomodulatory properties while not suppressing the immune in adults. DMF is sold for psoriasis treatment and sold as an oral formulation mixed with related compounds in Germany. In the UK, it is sold as a pure oral formulation. It is sold in the U.S. as an oral formulation to treat adults with relapsing multiple sclerosis. Dimethyl fumarate is sold under the brand name Skilarence & Tecfidera, just to name a few. Walter Schweckendiek, a German chemist first used fumaric acid, as a topical formulation for psoriasis in 1959. Fumapharm, The Swiss company, brought Fumaderm, an oral formulation of Dimethyl fumarate in Germany in 1994 to treat psoriasis.

Dosage and administration

Dimethyl fumarate is sold as 30 mg and 120 mg tablets. In the treatment of multiple sclerosis, the standard adult doses are 120 mg and 240 mg, with the maximum daily dose limited to 480 mg. The user is given a starting dose of 120 mg twice a day, orally. After a week, they are given a maintenance dose of 240 mg twice a day, orally. Reductions in dose are considered for individuals who do not tolerate the maintenance dose, however, the dosage should resume within 4 weeks. If users are unable to tolerate a return to the maintenance, the treatment is discontinued.

The cost of Dimethyl fumarate

In the UK, the annual cost of treatment on Dimethyl fumarate is £17,900 year. In the USA, the consumer has to pay an average retail price of $11,646.72 for a course of annual treatment.

How does Dimethyl fumarate work?

Dimethyl fumarate's main action is immunomodulation. This results in shifting T helper cells from the Th1 and Th17 profile to a Th2 phenotype. Dimethyl fumarates reduce the production of Inflammatory cytokines by inducting proapoptotic events. It also inhibits keratinocyte proliferation, reduces the expression of adhesion molecules in addition to diminishing the inflammatory infiltrate within psoriatic plaques. It is also shown to reduce the expression of micro-RNA-2. This is essential for producing pathogenic cells in multiple sclerosis and psoriasis. DMF achieves this through cell-permeable metabolites that epigenetically regulate the expression of micro-RNA-21, which it does through metabolic- epigenetic interplay during the development of immune cells in the body.

Finding DMF Manufacturers and Suppliers:

The process of finding trusted DMF manufacturers and DMF suppliers can be made quicker and more accessible by using Pipelinepharma's online platform, a B2B marketplace that lets you finalize the deals of pharmaceutical products in a matter of a few clicks. Also, it is an easy to use an online platform to grow your business opportunities. The robust search engine makes it convenient to search for manufacturers and suppliers of DMF. The search can be further refined with industry-specific filters such as dossier type, country of origin, GMP approvals, and search criteria for Wholesaler, etc. helping to get in contact with the preferred manufacturer and supplier readily.