Dextromethorphan Hydrobromide is used to get temporary relief from coughs without
phlegm, caused by specific infections of the airways, these infections affect the sinus and
common cold. It does not relieve the symptoms of coughing caused by smoking and it is also
not used in the management of long-term breathing ailments like chronic bronchitis or,
emphysema. The key ingredient is dextromethorphan which suppresses the need to cough
while lifting up the threshold for coughing. Dextromethorphan Hydrobromide in combination
with Promethazine HCl, in syrup, is also used to treat cough, itching, sneezing, discomfort in
the eyes caused by allergies. Dextromethorphan has a very little mu-opioid effect but exerts its
therapeutic effects through several other receptors
Dextromethorphan Hydrobromide is commonly sold under the brand names Benylin,
Creomulsion, Delsym amongst others.
Dextromethorphan Hydrobromide was tested by the US Army and CIA as a replacement for
Code-based medicines and approved for commercial use in 1957. However, the research on
its properties started in the early 1950s.
It may be used in generic labels and store brands, Benylin DM, Mucinex DM, Camydex-20
tablets, Robitussin, NyQuil, Dimetapp, Vicks, Coricidin, Delsym, TheraFlu, Charcoal D,
Cinfatós and others. It has been used in counterfeit medications.
Forms and dosage
In its pure form, dextromethorphan is sold as a white powder. The standard dose for antitussive
therapy is between 10 and 45 mg. The International Society for the Study of Cough
recommends that the first dose should be 60 mg in the adults and patients should avoid repeat
dosing. Given the forms and nature of ailments it is used to cure, it is available in different
strengths and is prescribed in different forms of different strengths depending on the disease.
The cost of Dextromethorphan Hydrobromide
It is sold as a powder. This powder costs an average of USD132 per kilo. The same quantity
sells for usd138 in the USA and USD194 in China.
How does it Dextromethorphan Hydrobromide work?
As any therapeutic, Dextromethorphan has a central effect on the brain, this elevates the
the threshold for coughing, without ciliary activity inhibition, as opposed to working locally or
directly on the respiratory tract.
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