Desmopressin is an antidiuretic medication used to treat diabetes insipidus, type A hemophilia, nocturnal enuresis, nocturia, and von Willebrand's disease. Desmopressin manufacturers produce medications with it in the form of tablets, oral suspensions, injectable solutions, and nasal sprays. In medical use for over 50 years, desmopressin has since become included in the World Health Organisation’s list of Essential Medicines that contains the safest and most effective drugs recommended for a health system. The drug is available across multiple geographic markets, from Europe to India, China, Mexico, and many others, while the largest manufacturers of desmopressin medications include Ferring Pharmaceuticals, Cadila Healthcare, Pfizer and Teva. Desmopressin suppliers and distributors market both generic and trade name formulations of the drug.
How Does Desmopressin Work?
Desmopressin stimulates adenylyl cyclase when it binds to V2 receptors on the basolateral membrane of cells in the distal tubule and collecting ducts of the nephron. The ensuing intracellular cascades in the collecting duct increase the rate of aquaporins—water channels—entering the lumenal membrane and improve the membrane's permeability to water. Desmopressin increases water re-absorption and decreases urine output by imitating the activities of endogenous ADH and acting as a selective agonist of V2 receptors found in the renal collecting duct (CD). In individuals with haemophilia and von Willebrand's disease Type I, desmopressin has been found to be more effective than ADH at raising plasma levels of factor VIII activity. Desmopressin exhibits significantly reduced pressor action. The antidiuretic action of desmopressin given orally is about one-tenth that of an identical dose given intravenously.
Wholesale Price of Desmopressin
Retail prices for the drug vary depending on desmopressin manufacturer and supplier pricing, specific formulation and on whether it is a generic or trade name variant of the drug. Costs per 30 (0.1mg) tablets of desmopressin can range from 30,00 EUR to 45,00 EUR, whereas the equivalent amount of 0.2mg tablets cost around 60,00 EUR. On the other hand, 2.5ml of the 0.1mg/ml desmopressin nasal spray costs around 15,00 EUR to 20,00 EUR. 10ml of the 15IU/ml desmopressin injectable solution is priced at around 300 EUR. Also the costs of Desmopressin vary depending on manufacturer and supplier pricing, whether it is a generic or trade name formulation, concentration of the active ingredient in the formulation. Desmopressin is available for sale from various Desmopressin vendors at multiple costs. Desmopressin suppliers, on the whole, are in favor of patient aid initiatives.
From Where to Get Desmopressin?
PipelinePharma is the most reliable source for this medication. Finding an honest partner in our business is one of the significant challenges. To overcome this challenge and make one's life easier when looking for a direct manufacturer and supplier of Desmopressin, one can go to the Pipelinepharma website, which assists buyers in locating dependable manufacturers and suppliers of Desmopressin. Buyers are advised that online sellers may attempt to market fraudulent versions of the generic drug, whereas Pipeline Pharma, through its pre-auditing and quality control procedures ensures that only verified Desmopressin manufacturers and wholesalers enter our online marketplace, offering you a risk-free B2B pharmaceutical sales platform.
Navigating our Pharmaceutical Marketplace
Being a global B2B pharmaceutical online marketplace, Pipelinepharma is structured to simplify pharmaceutical deals by providing you with an intuitive interface that is easy to engage with. The selection of Desmopressin offerings can be narrowed down with filters and easily weighed against one another according to medication prices and commercial terms. The advanced filters help you filter out the countries for this substance manufacturer and Desmopressin suppliers that you are looking for. These also enable you to check the dossier status of this medicine and the GMP approvals of the different variants of Desmopressin. Also, each manufacturer or supplier product description contains essential information about this substance, including clinical data, stability zones, and countries in which Desmopressin is already registered. Manufacturers also have special delivery terms.
Establishing Commercial Ties
Suppose you are a pharmaceutical licensing company or a distributor. In that case, you can enter into deals or negotiations over these medicine offers with manufacturing companies after completing the free registration process and joining our online marketplace. This helps ensure that you conclude the pharmaceutical deal at a reasonable cost and achieve the best cost/benefit ratio for your company while bypassing lengthy sourcing, negotiation, and order process. Once you have finalized a deal, you can look forward to a long-lasting business relationship with the Desmopressin suppliers. This way, the marketplace allows you as a distributor to skip the process of making a list of product manufacturers every time you are looking for in-licensing or distribution deals.
To keep up to the quality standards other than Good Manufacturing Practice approvals that this medicine manufacturers list has, we qualify their companies before they are boarded on the platform. This allows us to screen Desmopressin manufacturers for the quality of the pharmaceutical products' dossiers and protect against the risk of possible malpractices.